| Type | Description |
|---|---|
| Definition | gap junction protein, alpha 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:24:00 | Genetic deletion of connexin 37 causes polyuria and polydipsia. | 33332450 |
| 2020-07-25 12:12:00 | These findings provide evidence that Cx37 selectively influences Ang II signaling, mostly via a modulation of the expression of the Ang II type 2 receptor. | 30943815 |
| 2020-02-01 11:12:00 | Shear stress in the physiological range prevents inward remodeling in cultured arteries due to chronic constriction through an NO-, and specifically an eNOS-dependent, mechanism and increases connexin 37 expression. | 31574503 |
| 2018-07-14 10:41:00 | Diet-induced hyperhomocysteinemia enhanced myoendothelial feedback, and increased Cx37 and IK1 expression may contribute. nNOS or iNOS did not upregulate to compensate for decreased eNOS, and they had little involvement in vasomotor function. | 28857417 |
| 2018-03-03 10:55:00 | The presence of Cx37 in the media layer of injured arteries restrains vascular smooth muscle cell proliferation and limits the development of intimal hyperplasia, presumably by interfering with the pro-proliferative effect of Cx43 and the Akt pathway. | 28449099 |
| Type | IDs |
|---|---|
| Synonymous | AU020209, AW558810, Cnx37, Cx37, Gja-4 |
| Gene |
UniProtKB-ID:
CXA4_MOUSE,
Q3UPZ2_MOUSE
UniprotKB:
P28235,
Q3UPZ2
UniParc:
UPI00000264A8
EMBL:
AK143024,
AF216832,
X57971,
LT990380
Ensembl:
ENSMUSG00000050234
KO:
mmu:14612
|
| Nucleutide sequences |
EMBL-CDS:
AAF91221.1,
CAA41037.1,
BAE25252.1,
VZP20180.1
Ensembl_TRS:
ENSMUST00000053753
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000062320
RefSeq:
NP_032146.1
|
| Others |
UniRef100:
UniRef100_P28235
UniRef90:
UniRef90_Q03190
UniRef50:
UniRef50_Q03190
UniGene:
Mm.24615
CCDS:
CCDS18667.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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