| Type | Description |
|---|---|
| Definition | glial cell line derived neurotrophic factor family receptor alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:51:00 | GDNF and GFRalpha1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons. | 31875542 |
| 2020-06-27 10:07:00 | glial cell line-derived neurotrophic factor (GDNF) was identified as an essential factor for FGSCs self-renewal with a more complicated mechanism: GDNF-GFRA1 activates AKT3 via PI3K or Src family kinase (SFK), and SFK upregulates its target genes, Bcl6b, Etv5, and Lhx1, to promote self-renewal of Female germline stem cells. | 31041846 |
| 2019-06-08 11:56:00 | goblet cells may be a potential target for preventative treatment and that reduced expression of GFRa1 may contribute to Hirschsprung's disease susceptibility. | 30594740 |
| 2019-01-19 10:03:00 | these data provide support for a model of a stem cell pool in which the GFRa1+ and GFRa1- cells are closely related but show key cell-intrinsic differences and can interconvert between the two states based, in part, on access to niche factors. | 29337115 |
| 2018-12-22 10:28:00 | We further find that overexpression of NANOS2 results in the repression of GFRA1 and PLZF in gonocytes, leading to a delay in GST. On the other hand, loss of NANOS2 results in the up-regulation of GFRA1 and PLZF, indicating a precocious entry of GST. | 29339164 |
| Type | IDs |
|---|---|
| Synonymous | AU042498 |
| Gene |
UniProtKB-ID:
GFRA1_MOUSE
UniprotKB:
P97785
UniParc:
UPI0000022527,
UPI0000029477
EMBL:
CH466585,
AF015172,
AB000800,
AF014117,
BC054378
Ensembl:
ENSMUSG00000025089
KO:
mmu:14585
|
| Nucleutide sequences |
EMBL-CDS:
AAB86600.1,
AAB86599.1,
EDL01795.1,
BAA19185.1,
EDL01796.1,
AAH54378.1
Ensembl_TRS:
ENSMUST00000169850,
ENSMUST00000129100,
ENSMUST00000026076,
ENSMUST00000152507
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000130128,
ENSMUSP00000026076,
ENSMUSP00000120333,
ENSMUSP00000117196
RefSeq:
XP_006526744.1,
XP_030106613.1,
NP_001272386.1,
NP_034409.1,
XP_006526747.1,
XP_006526745.1,
XP_006526746.1
|
| Others |
UniRef100:
UniRef100_P97785
UniRef90:
UniRef90_Q62997
UniRef50:
UniRef50_Q62997
UniGene:
Mm.88367
CCDS:
CCDS70967.1,
CCDS38028.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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