| Type | Description |
|---|---|
| Definition | growth factor independent 1B |
| Date | Results | Publications |
|---|---|---|
| 2019-04-06 12:26:00 | Gfi1b regulates the level of Wnt3a/beta-catenin signaling in hematopoietic stem cells and megakaryocytes. | 30894540 |
| 2018-05-26 10:06:00 | We demonstrate that overexpression of Gfi1b, c-Fos, and Gata2, previously reported to transdifferentiate fibroblasts into hematopoietic progenitors in vitro, can induce long-term HSC formation in vivo. | 28943250 |
| 2018-01-13 11:30:00 | GFI1B is an essential protein for the normal development of the megakaryocyte lineage | 27122003 |
| 2017-07-08 10:17:00 | We conclude that Gfi1b controls major functions of megakaryocytes such as integrin-dependent cytoskeleton organization, spreading and migration through the regulation of PAK activity whereas the proplatelet formation defect in GFI1B-deficient megakaryocytes is due, at least partially, to an insufficient alpha-tubulin content. | 28082345 |
| 2016-10-08 10:42:00 | these results identify Rgs18 as a new and crucial effector of Gfi1b that regulates downstream signaling and gene expression programs to orchestrate erythro-megakaryocytic lineage choices. | 26567214 |
| Type | IDs |
|---|---|
| Synonymous | Gfi-1B |
| Gene |
UniProtKB-ID:
GFI1B_MOUSE,
B7ZNH2_MOUSE
UniprotKB:
O70237,
B7ZNH2
UniParc:
UPI00000229FF,
UPI000189A919
EMBL:
AL731851,
BC132367,
AF017275,
AK157262,
BC145238,
BC132365,
BC052654
Ensembl:
ENSMUSG00000026815
KO:
mmu:14582
|
| Nucleutide sequences |
EMBL-CDS:
AAI32366.1,
AAC40088.1,
AAH52654.1,
AAI32368.1,
BAE34016.1,
AAI45239.1
Ensembl_TRS:
ENSMUST00000028156,
ENSMUST00000164290
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028156,
ENSMUSP00000128052
RefSeq:
NP_001153878.1,
NP_032140.1
|
| Others |
UniRef100:
UniRef100_O70237,
UniRef100_B7ZNH2
UniRef90:
UniRef90_O70237
UniRef50:
UniRef50_O70237
UniGene:
Mm.373385
CCDS:
CCDS15843.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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