| Type | Description |
|---|---|
| Definition | growth differentiation factor 11 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:59:00 | Systemic GDF11 stimulates the secretion of adiponectin and induces a calorie restriction-like phenotype in aged mice. | 31637864 |
| 2020-07-04 12:21:00 | GDF11 promotes osteogenesis as opposed to MSTN, and follistatin, a MSTN/GDF11 inhibitor, increases muscle mass but weakens bone. | 32071240 |
| 2020-06-13 11:11:00 | GDF11, rather than globally acting as a morphogen secreted from the tail bud, locally regulates axial vertebral patterning. | 31183862 |
| 2020-03-28 10:13:00 | Targeted deletion of growth differentiation factor 11 in cardiomyocytes does not cause cardiac hypertrophy but rather leads to left ventricular dilation compared with control mice carrying only the Myh6-cre or growth differentiation factor 11-floxed alleles. | 31125255 |
| 2020-03-07 10:22:00 | Loss of Gdf11 specifically in the blood system does not impair hematopoietic stem cell function or induce overt pathological consequences. | 31530563 |
| Type | IDs |
|---|---|
| Synonymous | BMP-11, Bmp11 |
| Gene |
UniProtKB-ID:
GDF11_MOUSE
UniprotKB:
Q9Z1W4
UniParc:
UPI00000225D9
EMBL:
AF092734,
AF028337,
AF028336,
AF100904,
AF100905,
AF100906,
AF028335
Ensembl:
ENSMUSG00000025352
KO:
mmu:14561
|
| Nucleutide sequences |
EMBL-CDS:
AAC72853.1,
AAD05267.1,
AAF21633.1
Ensembl_TRS:
ENSMUST00000026408
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026408
RefSeq:
NP_034402.1
|
| Others |
UniRef100:
UniRef100_Q9Z1W4
UniRef90:
UniRef90_Q9Z1W4
UniRef50:
UniRef50_O14793
UniGene:
Mm.299218
CCDS:
CCDS24296.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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