| Type | Description |
|---|---|
| Definition | growth differentiation factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-09-17 10:55:00 | Epigenetic silencing of GDF1 abrogates the growth-inhibitory SMAD signaling and renders proliferation advantage to gastric epithelial cells during carcinogenesis | 26212015 |
| 2015-08-29 11:18:00 | GDF1 in the heart is a novel mediator that protects against the development of post-infarction cardiac remodelling via negative regulation of the MEK-ERK1/2 and Smad signalling pathways. | 25726944 |
| 2014-10-11 10:18:00 | This implies that Gdf1 potentiates Nodal activity by stabilizing a low molecular weight fraction that is susceptible to neutralization by soluble Acvr2. | 24798330 |
| 2014-04-19 11:52:00 | Data indicate that the expression of growth/differentiation factor 1 (GDF1) is up-regulated in human dilated cardiomyopathy (DCM)hearts and murine hypertrophic hearts. | 24275554 |
| 2010-01-21 00:00:00 | Results suggest that GDF1 and GDF3 together represent the functional mammalian homologs of Vg1. | 17936261 |
| Type | IDs |
|---|---|
| Synonymous | AI385651, Gdf-1 |
| Gene |
UniProtKB-ID:
GDF1_MOUSE,
Q3TRG1_MOUSE,
A2RT05_MOUSE
UniprotKB:
P20863,
Q3TRG1,
A2RT05
UniParc:
UPI0000026472,
UPI00005B1ED3,
UPI0000027E1B
EMBL:
BC132318,
AK162823,
M62301,
BC079555,
M57639
Ensembl:
ENSMUSG00000109523,
ENSMUSG00000087408
KO:
mmu:14559,
mmu:93898
|
| Nucleutide sequences |
EMBL-CDS:
AAA37674.1,
AAA37676.1,
AAH79555.1,
BAE37069.1,
AAI32319.1
Ensembl_TRS:
ENSMUST00000165819,
ENSMUST00000207684
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000146749,
ENSMUSP00000128325
RefSeq:
NP_032133.2,
NP_001156754.1
|
| Others |
UniRef100:
UniRef100_P20863,
UniRef100_P27545,
UniRef100_Q3TRG1
UniRef90:
UniRef90_P27545,
UniRef90_P20863
UniRef50:
UniRef50_P20863,
UniRef50_P27544
UniGene:
Mm.258280
CCDS:
CCDS52571.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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