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1455038 SSO_RS03895

1455038

SSO_RS03895

minichromosome maintenance protein MCM

protein-coding

Sulfolobus solfataricus P2

基因描述

Type Description
Definition minichromosome maintenance protein MCM

研究结论

Date Results Publications
2013-05-04 11:39:00 A newly identified function of MCM to change DNA topology may imply a wider functional role for MCM in DNA metabolisms in Sulfolobus solfataricus. 23361460
2010-01-21 00:00:00 MCM can tolerate catalytically inactive subunits and still function as a helicase, leading us to propose a semisequential model for helicase activity of this complex. 17964268
2010-01-21 00:00:00 A highly conserved threonine residue acts as a glutamate switch in the replicative helicase, MCM, and thus reveals that the glutamate switch is a feature common to all seven AAA+ clades. 19702328
2010-01-21 00:00:00 4.35-A crystal structure of the near-full-length ssoMCM; mutational analysis of residues at the intersubunit interfaces and around the side channels demonstrates their critical roles for hexamerization and helicase function 19073923
2010-01-21 00:00:00 GINS is important in coordinating the architecture of the replication fork and provides a mechanism to couple progression of the MCM helicase on the leading strand with priming events on the lagging strand. 16485022

名称对应

Type IDs
Synonymous SSO0774
Gene
Nucleutide sequences
Protein sequencees
RefSeq: WP_009991364.1
Others

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

University of Southern California

2
2

MRC Cancer Cell Unit, Hutchison MRC Research Centre, Hills Road, Cambridge, CB2 2XZ, UK.

1
3

MRC Cancer Cell Unit, Hutchison MRC Research Centre, Hills Road, Cambridge CB2 2XZ, UK.

1
4

Istituto di Biochimica delle Proteine, Consiglio Nazionale delle Ricerche, Via P. Castellino 111, 80131 Napoli, Italy.

1
5

Oxford University

1
热点人员
排名 研究人员 文献
1

Stephen D Bell

3
2

Xiaojiang S Chen

2
3

Adam T McGeoch

1
4

Matthew J Moreau

1
5

Alan R Lowe

1
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