| Type | Description |
|---|---|
| Definition | nuclear receptor subfamily 6, group A, member 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-01 11:35:00 | Here, the authors present the first structure of mouse GCNF DNA-binding domain in complex with the Oct4 DR0. The overall structure revealed two molecules bound in a head-to-tail fashion on opposite sides of the DNA at a DR0 motif located within the Oct4 promoter. | 27984042 |
| 2015-05-16 10:56:00 | Inactivation of the Gcnf gene in vivo leads to loss of repression of Oct4 expression in both male and female gonads. | 25140725 |
| 2015-01-10 14:14:00 | These results reveal that GCNF plays a key role in regulating activation of cyclin D1 expression via inhibition of Mir302a. | 24578347 |
| 2014-01-25 11:59:00 | Gcnf is expressed in fetal ovarian germ cells. | 23762465 |
| 2013-06-29 11:21:00 | characterize the let-7 target Nr6a1, an embryonic transcriptional repressor that regulates gene expression in adult fibroblasts following miRNA loss | 23630078 |
| Type | IDs |
|---|---|
| Synonymous | 1700113M01Rik, Gcnf, NCNF, RTR |
| Gene |
UniProtKB-ID:
NR6A1_MOUSE
UniprotKB:
Q64249
UniParc:
UPI0000000931,
UPI0001526375,
UPI0001526376
EMBL:
AF254815,
AF254818,
AF390899,
AF390896,
AF254821,
AF254817,
AF390898,
U09563,
U14666,
AF254820,
AF254816,
AF390900,
AF390897,
AF254575,
AF254819,
AL844842,
AL935155
Ensembl:
ENSMUSG00000063972
KO:
mmu:14536
|
| Nucleutide sequences |
EMBL-CDS:
AAM55193.1,
AAM95878.1,
AAA92682.1,
AAA64746.1,
AAG24485.1
Ensembl_TRS:
ENSMUST00000168098,
ENSMUST00000112877,
ENSMUST00000076275
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000126009,
ENSMUSP00000108498,
ENSMUSP00000075624
RefSeq:
XP_011237327.1,
NP_034394.1,
NP_001153020.1,
NP_001153021.1,
XP_036014313.1,
XP_036014311.1
|
| Others |
UniRef100:
UniRef100_Q64249
UniRef90:
UniRef90_Q64249
UniRef50:
UniRef50_Q64249
UniGene:
Mm.439703
CCDS:
CCDS50581.1,
CCDS16012.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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