| Type | Description |
|---|---|
| Definition | casein kinase 1 delta |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 12:59:00 | CRISPR-mediated gene targeting of CK1delta/epsilon leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1. | 32321936 |
| 2020-06-13 10:13:00 | Human Rad17 is constitutively phosphorylated in vivo on a C-terminal threonine, T670. Rad17-T670 is phosphorylated by casein kinase 1delta/epsilon. | 31353086 |
| 2020-05-09 10:28:00 | The effect of CK1delta/epsilon inhibition strongly depends on endogenous PER2 protein levels, which differs depending on both the molecular cause of the circadian disruption and the patient's lighting environment. | 31353796 |
| 2019-08-31 12:10:00 | Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D). | 31376410 |
| 2019-06-15 10:10:00 | X-ray crystallographic analysis of ligand-CK1delta complexes confirmed the expected binding mode of the 3,4-diaryl-isoxazole inhibitors. Surprisingly, the original compounds underwent spontaneous Pictet-Spengler cyclization with traces of formaldehyde during the co-crystallization process to form highly potent new ligands. | 30832206 |
| Type | IDs |
|---|---|
| Synonymous | ASPS, CKI-delta, CKId, CKIdelta, FASPS2, HCKID |
| Gene |
UniProtKB-ID:
KC1D_HUMAN
UniprotKB:
P48730
UniParc:
UPI000012DC64,
UPI0000071F44
EMBL:
BC003558,
U29171,
EF015900,
AK291758,
AB091044,
U31285,
BC015775
Ensembl:
ENSG00000141551
KO:
hsa:1453
|
| Nucleutide sequences |
EMBL-CDS:
BAC10903.1,
AAC50808.1,
ABM64211.1,
AAH15775.1,
AAC50807.1,
AAH03558.1,
BAF84447.1
Ensembl_TRS:
ENST00000392334,
ENST00000314028
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000324464,
ENSP00000376146
RefSeq:
NP_001884.2,
NP_620693.1,
XP_005256393.1,
NP_001350678.1
|
| Others |
UniRef100:
UniRef100_P48730
UniRef90:
UniRef90_P48730
UniRef50:
UniRef50_P48730
UniGene:
Hs.631725
CCDS:
CCDS11806.1,
CCDS11805.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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