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1450289 arfA

1450289

arfA

alternative ribosome-rescue factor A

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition alternative ribosome-rescue factor A

研究结论

Date Results Publications
2021-02-02 13:27:00 Molecular determinants of release factor 2 for ArfA-mediated ribosome rescue. 32727848
2019-01-12 10:51:00 Collectively, the findings indicate that MscL-dependent protein excretion is positively regulated in response to both osmotic stress and arfA-mediated translational stress. 29382730
2018-01-13 11:37:00 The structures demonstrate how ArfA 'senses' the vacant mRNA tunnel and activates RF2 to mediate peptide release without a stop codon, allowing stalled ribosomes to be recycled. 28300532
2017-07-15 11:22:00 ArfA binds within the ribosomal mRNA channel and substitutes for the absent stop codon in the A site by specifically recruiting release factor 2 (RF2), initially in a compact preaccommodated state. 27934701
2015-01-31 10:19:00 This study demonstrated the sites and modes of binding of ArfA to the stalled ribosome. 25355516

名称对应

Type IDs
Synonymous ECK3278, yhdL
Gene
UniProtKB-ID: ARFA_ECOLI
UniprotKB: P36675
UniParc: UPI000013B1F6
EMBL: AP009048, L29458, U18997, U00096
EnsemblGenome: b4550, BAE78000
KO: eco:b4550, ecj:JW3253
Nucleutide sequences
EMBL-CDS: AAA24772.1, BAE78000.1, ABD18700.1
EnsemblGenome_TRS: BAE78000, ABD18700
Protein sequencees
EnsemblGenome_PRO: ABD18700, BAE78000
RefSeq: YP_588467.1
Others
UniRef100: UniRef100_P36675
UniRef90: UniRef90_P36675
UniRef50: UniRef50_P36675

全选

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