| Type | Description |
|---|---|
| Definition | laccase domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:06:00 | LACC1 Required for NOD2-Induced, ER Stress-Mediated Innate Immune Outcomes in Human Macrophages and LACC1 Risk Variants Modulate These Outcomes. | 31875558 |
| 2019-11-16 10:39:00 | Our findings confirm that LACC1 variants can be responsible for the recessive form of juvenile arthritis. | 29717096 |
| 2018-12-22 10:13:00 | mRNA expression levels of both HIF1A and LACC1 were upregulated in the skin lesions of individuals with leprosy. | 29706348 |
| 2018-11-24 12:06:00 | LACC1 is critical for amplifying PRR-induced outcomes, an effect that is attenuated by the LACC1 disease-risk variant. | 28593945 |
| 2017-07-15 11:25:00 | FAMIN is a peroxisome-associated protein with primary role(s) in macrophages and other immune cells, where its metabolic functions may be modulated by PPAR signaling events | 27959965 |
| Type | IDs |
|---|---|
| Synonymous | C13orf31, FAMIN |
| Gene |
UniProtKB-ID:
LACC1_HUMAN
UniprotKB:
Q8IV20
UniParc:
UPI00000746BB
EMBL:
CH471075,
AL512506,
BC035749,
AK096044
Ensembl:
ENSG00000179630
KO:
hsa:144811
|
| Nucleutide sequences |
EMBL-CDS:
AAH35749.1,
BAC04686.1,
EAX08701.1
Ensembl_TRS:
ENST00000325686,
ENST00000441843
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000317619,
ENSP00000391747
RefSeq:
NP_001337571.1,
NP_001337569.1,
NP_001337568.1,
XP_024305087.1,
XP_024305088.1,
NP_001337575.1,
NP_001337570.1,
XP_011533237.1,
NP_001337572.1,
XP_024305089.1,
NP_001337567.1,
NP_694950.2,
NP_001337573.1,
XP_006719829.1,
NP_001337576.1,
NP_001337577.1,
NP_001121775.1,
NP_001337574.1
|
| Others |
UniRef100:
UniRef100_Q8IV20
UniRef90:
UniRef90_Q8IV20
UniRef50:
UniRef50_Q8IV20
UniGene:
Hs.210586
CCDS:
CCDS9391.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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