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14472 Gbx2

14472

Gbx2

gastrulation brain homeobox 2

protein-coding

Mus musculus

基因描述

Type Description
Definition gastrulation brain homeobox 2

研究结论

Date Results Publications
2017-10-21 12:04:00 Functional studies indicated that Klf4 mediates the self-renewal-promoting effects of Gbx2, because knockdown of Klf4 expression abrogated the ability of Gbx2 to maintain the undifferentiated state of mESCs. 28848051
2016-04-16 10:08:00 Deregulated FGF8 and Otx2/Gbx2 gene expression underlies cerebellar vermis hypoplasia in mouse model of CHARGE syndrome. 24368733
2016-02-27 11:15:00 Gbx2 is essential for the acquisition of the thalamic neuronal identity by repressing habenular identity through a feedback signaling from postmitotic neurons to progenitors 26297811
2013-11-02 10:23:00 Results reveal a novel function of Gbx2 in mESC reprogramming and LIF/Stat3-mediated self-renewal. 23345404
2013-06-01 10:06:00 Results indicate that the dynamic expression of Gbx2 may act as an important determinant in coupling with other developmental programs to generate distinct thalamic nuclei. 23056596

名称对应

Type IDs
Synonymous D130058E05Rik, Gbx-2, MMoxA, Stra7
Gene
UniProtKB-ID: GBX2_MOUSE
UniprotKB: P48031
UniParc: UPI0000024182
EMBL: BC120492, L39770, U74300, Z48800, BC116965, M81661
Ensembl: ENSMUSG00000034486
KO: mmu:14472
Nucleutide sequences
EMBL-CDS: AAA65185.1, AAC61877.1, AAI16966.1, AAI20493.1, AAA63314.1, CAA88737.1
Ensembl_TRS: ENSMUST00000036954
Protein sequencees
Ensembl_PRO: ENSMUSP00000048508
RefSeq: NP_034392.1
Others
UniRef100: UniRef100_P48031
UniRef90: UniRef90_P48031
UniRef50: UniRef50_P48031
UniGene: Mm.204730
CCDS: CCDS15150.1

全选

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研究热度

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