| Type | Description |
|---|---|
| Definition | F-box and leucine rich repeat protein 14 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 10:31:00 | FBXL14 acts as an novel interaction partner of CDCP1, and facilitates its ubiquitination and proteasomal degradation with an enhanced capacity to suppress CDCP1 protein stability that eventually prevents CDCP1 target genes involved in breast cancer metastasis. | 29973690 |
| 2019-02-09 11:50:00 | induced FBXL13 expression downregulates centrosomal gamma-tubulin and disrupts centrosomal microtubule arrays. In addition, depletion of FBXL13 induces high levels of CEP192 and gamma-tubulin at the centrosomes with the consequence of defects in cell motility. | 29348145 |
| 2017-08-12 12:07:00 | USP13 and FBXL14 play opposing roles in the regulation of glioma stem cells (GSCs) through reversible ubiquitination of c-Myc. | 27923907 |
| 2010-04-12 12:17:00 | Data show that Twist1 small interfering RNA prevents hypoxia-induced Fbxl14 down-regulation and SNAIL1 stabilization. | 19955572 |
| Type | IDs |
|---|---|
| Synonymous | Fbl14 |
| Gene |
UniProtKB-ID:
FXL14_HUMAN
UniprotKB:
Q8N1E6
UniParc:
UPI000006DA06
EMBL:
BC028132
Ensembl:
ENSG00000171823
KO:
hsa:144699
|
| Nucleutide sequences |
EMBL-CDS:
AAH28132.1
Ensembl_TRS:
ENST00000339235
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000344855
RefSeq:
NP_689654.1,
XP_016874365.1,
XP_016874364.1
|
| Others |
UniRef100:
UniRef100_Q8N1E6
UniRef90:
UniRef90_Q8N1E6
UniRef50:
UniRef50_Q8N1E6
UniGene:
Hs.367956
CCDS:
CCDS8509.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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