| Type | Description |
|---|---|
| Definition | guanylate binding protein 2b |
| Date | Results | Publications |
|---|---|---|
| 2019-11-23 10:19:00 | results indicate that GBP1 up-regulation and macrophage depletion can alleviate acute viral myocarditis-related cardial damage by inhibiting inflammatory responses and cardiomyocyte apoptosis while increasing cardiomyocyte viability | 30557035 |
| 2019-03-09 12:51:00 | Our results represent the presently most comprehensive information about expression of Gbps in leishmaniasis in vivo. We found that expression of Gbp2b/Gbp1 and Gbp5 is under strong genetic control involving in some strains also trans-regulation both in uninfected and L. major-infected mice. | 29467757 |
| 2018-12-22 11:54:00 | These observations suggest that Gbp1 may play an important role in protecting against mitochondrial dysfunction and preserving immune function of macrophages during inflammatory stress and aging. | 29374208 |
| 2016-02-20 11:15:00 | GBP1 GBP2 enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages. | 26416908 |
| 2014-01-11 11:38:00 | These findings demonstrate that Gbp1 plays an important role in the IFN-gamma-dependent, cell-autonomous control of toxoplasmosis and predict a broader role for this protein in host defense. | 23633952 |
| Type | IDs |
|---|---|
| Synonymous | Gbp-1, Gbp1, Mag-1, Mpa-1, Mpa1 |
| Gene |
UniProtKB-ID:
A4UUI2_MOUSE
UniprotKB:
A4UUI2
UniParc:
UPI0000022E3A
EMBL:
EF494422,
AC102108
Ensembl:
ENSMUSG00000040264
KO:
mmu:14468
|
| Nucleutide sequences |
EMBL-CDS:
ABO88215.1
Ensembl_TRS:
ENSMUST00000029936
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029936
RefSeq:
NP_034389.2,
XP_011238316.1,
XP_030108281.1
|
| Others |
UniRef100:
UniRef100_A4UUI2
UniRef90:
UniRef90_Q01514
UniRef50:
UniRef50_P32456
UniGene:
Mm.457978
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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