| Type | Description |
|---|---|
| Definition | fusion |
| Date | Results | Publications |
|---|---|---|
| 2017-09-02 11:38:00 | study found matrix (M) and F proteins each induced particle release when they were expressed alone but their coexpression led to coordinated assembly of virus-like particles (VLPs) that were morphologically and physically distinct from M-only or F-only VLPs; mutations to F protein transmembrane domain or cytoplasmic tail that disrupted endocytic trafficking led to failure of F to function with M for VLP assembly | 28468881 |
| 2017-06-03 11:38:00 | data suggest that the heptad repeat LIZ contributed to TM-TM association and is important for F protein function and pre-fusion stability. | 28213515 |
| 2012-04-28 11:04:00 | N-terminal end of the transmembrane domain of the F protein plays critical roles in fusion. | 22238302 |
| 2012-04-28 11:04:00 | Residues S490 and Y498 of F protein transmembrane domain are critical for endocytic recycling. | 22238299 |
| 2011-01-15 10:49:00 | Mutation of a histidine predicted to lie near the fusion peptide to alanine greatly reduced fusion despite wild-type cell surface expression levels, while asparagine substitution resulted in a moderate restoration in fusion levels. | 20702638 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
FUS_HENDH
UniprotKB:
O89342
UniParc:
UPI000017D13E
EMBL:
U49404,
AF017149
KO:
vg:1446467
|
| Nucleutide sequences |
EMBL-CDS:
AAC83192.2,
AAB39505.1
|
| Protein sequencees |
RefSeq:
NP_047111.2
|
| Others |
UniRef100:
UniRef100_O89342
UniRef90:
UniRef90_O89342
UniRef50:
UniRef50_Q9IH63
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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