| Type | Description |
|---|---|
| Definition | C-terminal Src kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 12:59:00 | Depletion of Csk preferentially reduces the protein level of LynA in a Cbl-dependent manner in cancer cells. | 32376886 |
| 2020-11-28 13:12:00 | CSK promotes innate immune response to DNA virus by phosphorylating MITA. | 32201077 |
| 2020-04-11 12:41:00 | CD28 functions as a novel adaptor protein for CSK, and CSK regulates signaling downstream of CD28 | 31292214 |
| 2019-12-21 10:15:00 | Here we report that Csk is covalently modified by SUMO1 at lysine 53 (K53) both in vitro and in vivo. Treatment with hydrogen peroxide inhibited this modification to a certain extent, but PIAS3, identified as the main specific SUMO E3 ligase for Csk, could significantly enhance SUMO1-Csk level | 31125786 |
| 2019-12-14 10:15:00 | results demonstrate that c-Src directly phosphorylates the Notch intracellular domain at specific tyrosine residues and that mutation of these phosphorylation sites increases Notch responsive transcriptional activity. | 30341382 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CSK_HUMAN,
B2R6Q4_HUMAN,
A8K3B6_HUMAN
UniprotKB:
P41240,
B2R6Q4,
A8K3B6
UniParc:
UPI00015DA78C,
UPI0000128541
EMBL:
AK312669,
X74765,
AK127672,
CR541960,
DQ075211,
X59932,
BC106073,
BC104847,
BC104875,
CH471136,
X60114,
AK290531
Ensembl:
ENSG00000103653
KO:
hsa:1445
|
| Nucleutide sequences |
EMBL-CDS:
CAA42556.1,
CAG46758.1,
AAI04876.1,
AAY57329.1,
AAI06074.1,
CAB58562.1,
AAI04848.1,
CAA42713.1,
EAW99311.1,
EAW99312.1,
BAG35551.1,
BAG54548.1,
BAF83220.1
Gene_ORFName:
hCG_40804
Ensembl_TRS:
ENST00000220003,
ENST00000439220,
ENST00000567571
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000414764,
ENSP00000454906,
ENSP00000220003
RefSeq:
NP_001374027.1,
NP_001374023.1,
NP_001374019.1,
NP_001374020.1,
NP_001374022.1,
NP_001341917.1,
NP_001374025.1,
NP_001374026.1,
NP_001374021.1,
NP_001374024.1,
NP_004374.1,
NP_001374018.1,
NP_001120662.1
|
| Others |
UniRef100:
UniRef100_P41240,
UniRef100_A8K3B6
UniRef90:
UniRef90_P41240
UniRef50:
UniRef50_P41240
UniGene:
Hs.77793
CCDS:
CCDS10269.1
|