| Type | Description |
|---|---|
| Definition | galanin receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 11:06:00 | These data demonstrate that Galanin (Gal) contributes not only to cholangiocyte proliferation but also to liver fibrogenesis via the coordinate activation of GalR1 in cholangiocytes and GalR2 in hepatic stellate cells (HSCs). | 31953035 |
| 2017-07-29 10:38:00 | In the present study, the functional coupling of Gi/o protein-coupled receptors to GalR1, and the CB1 receptor subtype for endocannabinoids were analyzed in the 3xTg-AD mice model of Alzheimer's disease in the prodromal and advanced stages. In addition, the activity mediated by Gi/o protein-coupled M2/4 muscarinic receptor subtypes was also analyzed in brain areas involved in anxiety and cognition. | 27223629 |
| 2016-12-17 10:16:00 | Galanin, acting via the GAL1 receptor and Gi -coupled signalling in L and K cells, is a potent inhibitor of GLP-1 and GIP secretion | 26661062 |
| 2016-02-06 11:31:00 | endogenous Gal-1 may influence T. cruzi infection by fueling tolerogenic circuits that hinder anti-parasite immunity. | 26324777 |
| 2016-01-16 11:12:00 | Experiments with a GalR1-preffering galanin analog, NAX-5055, show that GalR1 is involved in regulating glucose and insulin homeostasis | 25690510 |
| Type | IDs |
|---|---|
| Synonymous | Galnr1 |
| Gene |
UniProtKB-ID:
GALR1_MOUSE
UniprotKB:
P56479
UniParc:
UPI00000223A4
EMBL:
Y15004,
U90657,
U90655,
U90656
Ensembl:
ENSMUSG00000024553
KO:
mmu:14427
|
| Nucleutide sequences |
EMBL-CDS:
CAA75237.1,
AAB87748.1
Ensembl_TRS:
ENSMUST00000065224
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000066381
RefSeq:
NP_032108.1
|
| Others |
UniRef100:
UniRef100_P56479
UniRef90:
UniRef90_Q62805
UniRef50:
UniRef50_P47211
UniGene:
Mm.6219
CCDS:
CCDS29372.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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