| Type | Description |
|---|---|
| Definition | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-09 11:36:00 | Study analyzed enzyme activity and intracellular localization of the products of mutant cDNAs from eleven cases of hereditary spastic paraplegia with mutation in the coding region of B4GALNT1, and noted a lack of enzyme activity in a majority of them except two family cases. Then compared profiles of clinical findings of patients with hereditary spastic paraplegia and abnormal phenotypes of B4galnt-KO mice. | 30521973 |
| 2018-01-06 10:57:00 | We used GM2/GD2 synthase (B4galnt1)-deficient mice to immunize by liposomes embedded with GD1alpha or acidic glycolipid fractions from brain of St3gal5-deficient mice. Specificities of established mAbs as analyzed by enzyme-linked immunosorbent assay and thin-layer chromatography-immunostaining were very high among various gangliosides. | 27102283 |
| 2016-04-30 11:30:00 | GM2 elevation is associated with activation of microglia and astrocytes in the injured developing brain, and GM2, GD2, or other downstream gangliosides may regulate astroglial responses in ethanol-induced neurodegeneration | 26063460 |
| 2014-12-06 11:21:00 | This study demonistrated that Ganglioside deficiency(B4galnt1 and ST8SIA1 knockout mice causes inflammation and neurodegeneration via the activation of complement system in the spinal cord. | 24673754 |
| 2013-04-20 10:29:00 | Galgt1 is required for presynaptic expression of the CT carbohydrate at the neuromuscular junction. | 22982027 |
| Type | IDs |
|---|---|
| Synonymous | 4933429D13Rik, Gal-NAc-T, GalNAc-T, GalNAcT, Galgt1, Ggm-2, Ggm2 |
| Gene |
UniProtKB-ID:
B4GN1_MOUSE,
Q3UN35_MOUSE,
Q8VDF0_MOUSE,
A0A1Z4EAV4_MOUSE
UniprotKB:
Q09200,
Q3UN35,
Q8VDF0,
A0A1Z4EAV4
UniParc:
UPI0000001ABA,
UPI000154BEA4,
UPI00000E837C
EMBL:
BC036996,
BC057199,
U18975,
AK144484,
LC273292,
L25885,
BC022180
Ensembl:
ENSMUSG00000006731
KO:
mmu:14421
|
| Nucleutide sequences |
EMBL-CDS:
AAH57199.1,
AAA85496.1,
AAA65027.1,
AAH36996.1,
BAE25913.1,
AAH22180.1,
BAX90093.1
Ensembl_TRS:
ENSMUST00000006914
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000006914
RefSeq:
NP_082015.2,
NP_032106.1,
XP_017169292.1,
NP_001231546.1,
NP_001345506.1,
XP_006513282.1,
NP_001345507.1,
NP_001231547.1
|
| Others |
UniRef100:
UniRef100_Q8VDF0,
UniRef100_Q09200
UniRef90:
UniRef90_Q8VDF0,
UniRef90_Q09200
UniRef50:
UniRef50_Q00973,
UniRef50_Q00973-3
UniGene:
Mm.386762
CCDS:
CCDS24230.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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