| Type | Description |
|---|---|
| Definition | solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:30:00 | Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects. | 32248400 |
| 2019-06-29 12:51:00 | GAT-2 deficiency promotes Th17 cell responses through activation of GABA-mTOR signaling | 30523310 |
| 2013-01-05 10:55:00 | Deletion of the gamma-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents. | 22896705 |
| 2012-03-17 11:44:00 | This study suggests that BGT1 plays its main role in the liver, thereby complementing other betaine-transporting carrier proteins (e.g., slc6a20) that are predominantly expressed in the small intestine or kidney rather than the liver. | 22071246 |
| 2011-10-22 10:25:00 | Mice lacking exons 3-5 of the BGT1 gene have normal development & show seizure susceptibility indistinguishable from wild-type in a variety of seizure threshold models. This does not support a role for BGT1 in the control of seizure susceptibility. | 21459558 |
| Type | IDs |
|---|---|
| Synonymous | BGT1, GAT-2, GAT2, Gabt2 |
| Gene |
UniProtKB-ID:
G5E8Z4_MOUSE,
Q8VCS9_MOUSE
UniprotKB:
G5E8Z4,
Q8VCS9
UniParc:
UPI00000233C3,
UPI0000D5B848
EMBL:
BC019211,
AC153982
Ensembl:
ENSMUSG00000030109
KO:
mmu:14411
|
| Nucleutide sequences |
EMBL-CDS:
AAH19211.2
Ensembl_TRS:
ENSMUST00000166457,
ENSMUST00000032200
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000126937,
ENSMUSP00000032200
RefSeq:
NP_001368834.1,
XP_006505599.1,
NP_001368832.1,
NP_001334362.1,
NP_001368835.1,
NP_598422.2,
NP_001368833.1
|
| Others |
UniRef100:
UniRef100_Q8VCS9
UniRef90:
UniRef90_P31651
UniRef50:
UniRef50_P48065
UniGene:
Mm.274506
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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