| Type | Description |
|---|---|
| Definition | pleckstrin homology domain containing A7 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:53:00 | Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33. | 32371390 |
| 2018-03-10 11:49:00 | Downregulation of PLEKHA7 in PACG may affect BAB integrity and aqueous humor outflow via its Rac1/Cdc42 GAP activity, thereby contributing to disease etiology. | 29016860 |
| 2016-12-17 10:44:00 | our findings support a multi-layered role of PLEKHA7 in converging cytoskeletal dynamics and miRNA-mediated growth regulation at the ZA, with potentially critical implications in cancer that warrant further investigation. | 26822694 |
| 2016-11-12 11:50:00 | These results show that the PLEKHA7-PDZD11 complex stabilizes nectins to promote efficient early junction assembly and uncover a new molecular mechanism through which PLEKHA7 recruits PDZ-binding membrane proteins to epithelial adherens junctions. | 27044745 |
| 2016-11-05 12:00:00 | Familial linkage studies for primary angle-closure glaucoma have been performed and identified PLEKHA7 causative primary glaucoma disease | 26497787 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PKHA7_HUMAN,
E9PKC0_HUMAN
UniprotKB:
Q6IQ23,
E9PKC0
UniParc:
UPI00017A7211,
UPI0000456498,
UPI0001F78693,
UPI0001838858
EMBL:
BC033239,
AK301465,
AK296371,
AC026639,
AC116533,
AC127033,
BC071599,
AC131064
Ensembl:
ENSG00000166689
KO:
hsa:144100
|
| Nucleutide sequences |
EMBL-CDS:
AAH33239.1,
BAG59045.1,
BAG62985.1,
AAH71599.1
Ensembl_TRS:
ENST00000355661,
ENST00000531066
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000347883,
ENSP00000435389
RefSeq:
XP_024304128.1,
XP_024304138.1,
XP_024304136.1,
NP_778228.3,
XP_024304129.1,
XP_024304127.1,
NP_001316560.1,
XP_024304130.1,
XP_024304134.1,
XP_024304131.1,
NP_001316559.1,
XP_024304137.1,
XP_024304125.1,
XP_016872731.1,
XP_024304132.1,
XP_024304135.1,
XP_024304133.1,
XP_016872730.1,
XP_024304126.1,
XP_024304124.1
|
| Others |
UniRef100:
UniRef100_E9PKC0,
UniRef100_Q6IQ23
UniRef90:
UniRef90_Q6IQ23
UniRef50:
UniRef50_Q6IQ23
UniGene:
Hs.12332
CCDS:
CCDS31434.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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