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14406 Gabrg2

14406

Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

protein-coding

Mus musculus

基因描述

Type Description
Definition gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

研究结论

Date Results Publications
2021-02-06 13:59:00 Endoplasmic reticulum stress increases inflammatory cytokines in an epilepsy mouse model Gabrg2(+/Q390X) knockin: A link between genetic and acquired epilepsy? 32944937
2020-04-11 12:46:00 these data demonstrate the molecular basis for a comorbidity of epilepsy, anxiety, and suggest that impaired GABAA receptor function in CeA due to a loss-of-function mutation could at least contribute to anxiety 31087664
2019-02-09 10:20:00 deletion of Gabrg2 on dopamine cells induced several behavioral traits associated with high risk of developing alcoholism. 29463910
2018-05-19 11:12:00 This study found that the inactivation of gamma2-mediated synapses does not impact oligodendrocyte precursors proliferation and differentiation or the propensity of oligodendrocyte precursors to myelinate their presynaptic interneurons. 28795438
2018-02-03 11:19:00 The results of this study suggesting that mutations like GABRG2(Q390X) may alter brain thermal regulation and precipitate seizures during temperature elevations. 28505490

名称对应

Type IDs
Synonymous GABAA-R, Gabrg-2, gamma2
Gene
UniProtKB-ID: GBRG2_MOUSE
UniprotKB: P22723
UniParc: UPI0000001522, UPI000002AA2F
EMBL: AF233781, AF233797, AF233778, AF233795, AF233796, AF233802, AF233786, AF233776, AF233788, AF233784, AF233790, BC031762, AF233782, AF233780, M86572, AF233800, AF233801, M62374, AF233783, AF233794, AF233787, AF233799, AF233798, AF233789, AF233785, AF233775, AF233779, AF233793, AF233777, AF233792, AF233791
Ensembl: ENSMUSG00000020436
KO: mmu:14406
Nucleutide sequences
EMBL-CDS: AAK71592.1, AAK71576.1, AAK71596.1, AAK71600.1, AAK71595.1, AAK71591.1, AAK71598.1, AAB59635.1, AAK71593.1, AAK71586.1, AAK71599.1, AAK71575.1, AAK71581.1, AAK71589.1, AAK71577.1, AAK71588.1, AAA37653.1, AAK71580.1, AAK71597.1, AAK71594.1, AAK71574.1, AAK71585.1, AAH31762.1, AAK71590.1, AAK71573.1, AAK71587.1, AAK71579.1, AAK71578.1, AAK71584.1, AAK71583.1, AAK71582.1
Ensembl_TRS: ENSMUST00000070735, ENSMUST00000070725
Protein sequencees
Ensembl_PRO: ENSMUSP00000064739, ENSMUSP00000063812
RefSeq: XP_030101421.1, NP_001349585.1, NP_803127.3, NP_001349584.1, XP_036012226.1, NP_032099.1
Others
UniRef100: UniRef100_P22723
UniRef90: UniRef90_P22723
UniRef50: UniRef50_P22723
UniGene: Mm.5309
CCDS: CCDS24551.1, CCDS24552.2

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研究热度

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