| Type | Description |
|---|---|
| Definition | gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:53:00 | Protrudin modulates seizure activity through GABAA receptor regulation. | 31772151 |
| 2019-12-14 10:12:00 | The results reveal that furin may regulate GABA-A receptors-mediated inhibitory synaptic transmission by altering the transcription of Gabrb2 and Gabrb3 subunits in epilepsy. | 30333479 |
| 2019-11-16 11:13:00 | Loss of either GABAA receptors (GABAARs) or NMDA receptors (NMDARs) in primary afferents leads to tactile hypersensitivity across skin types, and loss of GABAARs, but not NMDARs, leads to impaired texture discrimination. | 30826183 |
| 2019-08-03 10:07:00 | In inhibitory transmission onto hippocampal CA1 pyramidal cells, deletion of all beta subunits 1, 2, and 3 completely eliminated inhibitory responses. In addition, only knockout of beta3, alone or in combination with another beta subunit, impaired inhibitory synaptic transmission. expression of beta3 alone on the background of the beta1-3 subunit knockout was sufficient to restore synaptic and extrasynaptic inhibitory ... | 29706582 |
| 2017-11-26 00:38:00 | These results suggest that impairment in GABRB3 downregulates OCA2 and indirectly causes ocular hypopigmentation and visual defects in Angelman syndrome (AS) and Prader-Willi syndrome | 28009282 |
| Type | IDs |
|---|---|
| Synonymous | A230092K12Rik, AW049585, Cp1, Gabrb-3, beta3 |
| Gene |
UniProtKB-ID:
GBRB3_MOUSE,
Q8C446_MOUSE
UniprotKB:
P63080,
Q8C446
UniParc:
UPI0000004016,
UPI00000E9E46
EMBL:
U14420,
AC160553,
AC102129,
AC102236,
AC158300,
AC109157,
AK039070,
AK147247,
AK083107
Ensembl:
ENSMUSG00000033676
KO:
mmu:14402
|
| Nucleutide sequences |
EMBL-CDS:
AAB60502.1,
BAC30230.1,
BAE27794.1,
BAC38763.1
Ensembl_TRS:
ENSMUST00000039697,
ENSMUST00000196198
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000038051,
ENSMUSP00000143353
RefSeq:
NP_001033790.1,
NP_032097.1
|
| Others |
UniRef100:
UniRef100_Q8C446,
UniRef100_P63080
UniRef90:
UniRef90_P28472
UniRef50:
UniRef50_P28472
UniGene:
Mm.8004
CCDS:
CCDS21324.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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