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14401 Gabrb2

14401

Gabrb2

gamma-aminobutyric acid (GABA) A receptor, subunit beta 2

protein-coding

Mus musculus

基因描述

Type Description
Definition gamma-aminobutyric acid (GABA) A receptor, subunit beta 2

研究结论

Date Results Publications
2020-09-05 13:53:00 Protrudin modulates seizure activity through GABAA receptor regulation. 31772151
2019-12-14 10:12:00 The results reveal that furin may regulate GABA-A receptors-mediated inhibitory synaptic transmission by altering the transcription of Gabrb2 and Gabrb3 subunits in epilepsy. 30333479
2019-08-03 10:07:00 In inhibitory transmission onto hippocampal CA1 pyramidal cells, deletion of all beta subunits 1, 2, and 3 completely eliminated inhibitory responses. In addition, only knockout of beta3, alone or in combination with another beta subunit, impaired inhibitory synaptic transmission. expression of beta3 alone on the background of the beta1-3 subunit knockout was sufficient to restore synaptic and extrasynaptic inhibitory ... 29706582
2019-02-09 11:42:00 These extensive schizophrenia-like and comorbid phenotypes brought about by Gabrb2 knockout, in conjunction with our previous findings on GABRB2 association with schizophrenia, support a pivotal role of GABRB2 in schizophrenia etiology. 30013074
2016-04-16 10:40:00 Rebound potentiation is an input-specific plasticity that occurs only at basket cell-Purkinje cell inhibitory synapses and critically relies on GABAA receptors containing the beta2-subunit. 26179122

名称对应

Type IDs
Synonymous AI834970, C030002O17Rik, C030021G16Rik, Gabrab2, Gabrb-2
Gene
UniProtKB-ID: GBRB2_MOUSE
UniprotKB: P63137
UniParc: UPI00000041E5, UPI0001BC2644
EMBL: BC145975, GU086167, AL645964, BC145973, CH466609, AK090279, U14419, AL627444
Ensembl: ENSMUSG00000007653
KO: mmu:14401
Nucleutide sequences
EMBL-CDS: ACY69098.1, AAI45974.1, AAA79974.1, EDL32344.1, AAI45976.1, BAC41155.1
Ensembl_TRS: ENSMUST00000007797, ENSMUST00000192403
Protein sequencees
Ensembl_PRO: ENSMUSP00000007797, ENSMUSP00000141868
RefSeq: NP_001349575.1, NP_001334243.1, XP_030101420.1, NP_001349576.1, NP_001349578.1, NP_032096.1
Others
UniRef100: UniRef100_P63137
UniRef90: UniRef90_P63137
UniRef50: UniRef50_P47870
UniGene: Mm.338723, Mm.471870
CCDS: CCDS88146.1, CCDS24555.1

全选

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