| Type | Description |
|---|---|
| Definition | gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 10:07:00 | In inhibitory transmission onto hippocampal CA1 pyramidal cells, deletion of all beta subunits 1, 2, and 3 completely eliminated inhibitory responses. In addition, only knockout of beta3, alone or in combination with another beta subunit, impaired inhibitory synaptic transmission. expression of beta3 alone on the background of the beta1-3 subunit knockout was sufficient to restore synaptic and extrasynaptic inhibitory ... | 29706582 |
| 2016-09-24 11:26:00 | Results indicate that GABAB1a and GABAB1b isoforms differentially regulate behavioural responses to cocaine, with deletion of GABAB1a enhancing cocaine-induced locomotor activity and deletion of GABAB1b protecting from cocaine-induced sensitisation | 26518330 |
| 2015-08-22 10:42:00 | Study of GABAB1 KO mice provides genetic evidence for a specific involvement of GABAB receptors in the regulation of the behavioral and biochemical effects induced by nicotine withdrawal in mice | 25479464 |
| 2014-07-19 11:50:00 | Heritable preference for ethanol results from a dominant mutation L285R; P228H also causes high ethanol consumption | 24281383 |
| 2013-11-16 11:20:00 | we conclude that is a greater contribution of beta(1) -subunit-containing GABA(A) receptors following oxygen and glucose deprivation in cerebellar Purkinje cells | 23176253 |
| Type | IDs |
|---|---|
| Synonymous | AW061132, B230208N19Rik, Gabrb-1 |
| Gene |
UniProtKB-ID:
GBRB1_MOUSE,
Q53WT3_MOUSE
UniprotKB:
P50571,
Q53WT3
UniParc:
UPI0000000688
EMBL:
BC130258,
BC157920,
U14418,
X55273
Ensembl:
ENSMUSG00000029212
KO:
mmu:14400
|
| Nucleutide sequences |
EMBL-CDS:
AAA79973.1,
AAI57921.1,
CAA38993.1,
AAI30259.1
Ensembl_TRS:
ENSMUST00000031122
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000031122
RefSeq:
NP_001357897.1,
NP_032095.1
|
| Others |
UniRef100:
UniRef100_P50571
UniRef90:
UniRef90_P15431
UniRef50:
UniRef50_P15431
UniGene:
Mm.38567
CCDS:
CCDS19329.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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