| Type | Description |
|---|---|
| Definition | colony stimulating factor 2 receptor alpha subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:53:00 | Expression of granulocyte macrophage-colony stimulating factor and its receptor in the synovium of osteoarthritis patients is negatively correlated with pain. | 32365364 |
| 2020-05-09 10:29:00 | These data show that loss of membrane GM-CSFRalpha following GM-CSF exposure does not preclude sustained GM-CSF/GM-CSFRalpha signaling and that this receptor plays a key role in ligand clearance. Hence neutrophilic activation via GM-CSFR may play an important role in neutrophilic lung inflammation even in the absence of high GM-CSF levels or GM-CSFRalpha expression. | 30942918 |
| 2020-02-01 10:18:00 | Missense mutations in CSF2RA gene is associated with Pediatric Crohn's Disease. | 30124884 |
| 2018-11-03 11:22:00 | Family-based whole genome analysis of a family with hereditary pulmonary alveolar proteinosis revealed a homozygous deletion that disrupts CSF2RA, CRLF2, and IL3RA gene in the pseudoautosomal region of the X chromosome in the affected child and one of asymptomatic siblings. | 28233860 |
| 2018-06-02 12:07:00 | lesions from human secondary progressive multiple sclerosis, but not primary progressive multiple sclerosis patients shows extensive recruitment of GM-CSF Ralpha+ myeloid cells | 28641926 |
| Type | IDs |
|---|---|
| Synonymous | CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4, alphaGMR |
| Gene |
UniProtKB-ID:
CSF2R_HUMAN
UniprotKB:
P15509
UniParc:
UPI000002AAA2,
UPI000002AAA1,
UPI000002AAA4,
UPI00017A8219,
UPI000159C3E4,
UPI0000000C45,
UPI000002AAA0,
UPI000015FCE5
EMBL:
M64445,
AK293086,
DQ841258,
L29348,
BX649553,
L29349,
X54935,
M73832,
BC071835,
X17648,
BC002635,
D26628,
U93096,
AK301395
Ensembl:
ENSG00000198223
KO:
hsa:1438
|
| Nucleutide sequences |
EMBL-CDS:
AAA35909.1,
AAA60962.1,
BAG62930.1,
AAH02635.1,
CAA38697.1,
AAH71835.1,
CAA35638.1,
AAA35908.1,
BAF85775.1,
AAB51535.1,
BAA05656.1,
AAA60961.1,
ABI32309.1
Ensembl_TRS:
ENST00000381529,
ENST00000355432,
ENST00000381524,
ENST00000417535,
ENST00000501036,
ENST00000381509,
ENST00000381500,
ENST00000432318,
ENST00000355805
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000370911,
ENSP00000370935,
ENSP00000440491,
ENSP00000394227,
ENSP00000416437,
ENSP00000370920,
ENSP00000348058,
ENSP00000370940,
ENSP00000347606
RefSeq:
NP_001366095.1,
NP_001366093.1,
NP_758450.1,
XP_011543925.1,
NP_001366092.1,
NP_001366087.1,
NP_001366094.1,
NP_001366083.1,
NP_758449.1,
NP_001366098.1,
XP_011544476.1,
XP_011543930.1,
NP_001155003.1,
XP_011544471.1,
NP_001366084.1,
XP_011544469.1,
NP_001155001.1,
XP_011544472.1,
NP_006131.2,
NP_001366097.1,
NP_758448.1,
NP_001366088.1,
NP_001366096.1,
NP_001366085.1,
NP_001366090.1,
XP_011543922.1,
NP_001366082.1,
NP_001155002.1,
NP_001155004.1,
XP_011544477.1,
XP_011543924.1,
NP_001366089.1,
XP_011544467.1,
XP_011543929.1,
XP_011543920.1,
NP_758452.1,
NP_001366091.1
|
| Others |
UniRef100:
UniRef100_P15509
UniRef90:
UniRef90_P15509
UniRef50:
UniRef50_P15509
UniGene:
Hs.520937
CCDS:
CCDS55361.1,
CCDS35190.1,
CCDS35191.1,
CCDS55360.1,
CCDS55359.1,
CCDS35192.1,
CCDS35193.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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