例如:"NBL1", "4681", "drought"
收藏
14375 Xrcc6

14375

Xrcc6

X-ray repair complementing defective repair in Chinese hamster cells 6

protein-coding

Mus musculus

基因描述

Type Description
Definition X-ray repair complementing defective repair in Chinese hamster cells 6

研究结论

Date Results Publications
2021-02-27 13:47:00 C-Terminal Extensions of Ku70 and Ku80 Differentially Influence DNA End Binding Properties. 32937838
2019-07-27 11:44:00 our results reveal and the Ku70/80 complex as critical DNA double-strand breaks (DSBs) sensors, and suggest that Pduanyu371 may function as an important regulator of the Ku70/80 complex at the DSBs in the S/G2 phase. 29447383
2018-07-07 12:25:00 Data show that phosphorylated Ku70 S155 interacts with the Aurora B kinase and leads to inhibition of its activity. 27849008
2017-12-30 10:02:00 Ku70 is epistatic with XLF and DNA-PKcs and support a model in which inactivation of Ku70 allows DNA lesions to become accessible to alternative DNA repair pathways (other than Classical Non-Homologous End-Joining (C-NHEJ)). 28759779
2017-06-12 13:04:00 Study found that emphysema occurred in ku70(-/-) mice at the age of three-months old, and that Bax deficiency was able to suppress it. These results suggest that Bax-mediated apoptosis induces emphysema in ku70(-/-) mice. 27302174

名称对应

Type IDs
Synonymous 70kDa, G22p1, Ku70
Gene
UniProtKB-ID: XRCC6_MOUSE, A0A0R4J187_MOUSE
UniprotKB: P23475, A0A0R4J187
UniParc: UPI0000021F06, UPI0000001A86
EMBL: AK146394, AF483500, U50374, U50376, U50369, AK146392, U50377, AK143570, AF483501, U50372, AC102176, U50370, M38700, U50378, U50375, BC031422, U34878, AB010282, Z14157, U50373, U50368, AK146396, U50367, U50371
Ensembl: ENSMUSG00000022471
KO: mmu:14375
Nucleutide sequences
EMBL-CDS: AAH31422.1, BAE27139.1, BAE25441.1, AAC53575.1, AAC52675.1, BAE27137.1, BAA28874.1, AAL90774.1, AAA39396.1, CAA78526.1, AAL90775.1, BAE27135.1
Ensembl_TRS: ENSMUST00000069530, ENSMUST00000100399
Protein sequencees
Ensembl_PRO: ENSMUSP00000068559, ENSMUSP00000097968
RefSeq: XP_006520505.1, XP_011243758.1, NP_034377.2, XP_006520506.1, XP_006520507.1, XP_006520508.1
Others
UniRef100: UniRef100_P23475, UniRef100_A0A0R4J187
UniRef90: UniRef90_P23475
UniRef50: UniRef50_P12956
UniGene: Mm.288809
CCDS: CCDS37153.1

全选

研究热度

热点单位
热点人员
已经存在同名检索词。
检索词名称不能为空。