Type | Description |
---|---|
Definition | X-ray repair complementing defective repair in Chinese hamster cells 6 |
Date | Results | Publications |
---|---|---|
2021-02-27 13:47:00 | C-Terminal Extensions of Ku70 and Ku80 Differentially Influence DNA End Binding Properties. | 32937838 |
2019-07-27 11:44:00 | our results reveal and the Ku70/80 complex as critical DNA double-strand breaks (DSBs) sensors, and suggest that Pduanyu371 may function as an important regulator of the Ku70/80 complex at the DSBs in the S/G2 phase. | 29447383 |
2018-07-07 12:25:00 | Data show that phosphorylated Ku70 S155 interacts with the Aurora B kinase and leads to inhibition of its activity. | 27849008 |
2017-12-30 10:02:00 | Ku70 is epistatic with XLF and DNA-PKcs and support a model in which inactivation of Ku70 allows DNA lesions to become accessible to alternative DNA repair pathways (other than Classical Non-Homologous End-Joining (C-NHEJ)). | 28759779 |
2017-06-12 13:04:00 | Study found that emphysema occurred in ku70(-/-) mice at the age of three-months old, and that Bax deficiency was able to suppress it. These results suggest that Bax-mediated apoptosis induces emphysema in ku70(-/-) mice. | 27302174 |
Type | IDs |
---|---|
Synonymous | 70kDa, G22p1, Ku70 |
Gene |
UniProtKB-ID:
XRCC6_MOUSE,
A0A0R4J187_MOUSE
UniprotKB:
P23475,
A0A0R4J187
UniParc:
UPI0000021F06,
UPI0000001A86
EMBL:
AK146394,
AF483500,
U50374,
U50376,
U50369,
AK146392,
U50377,
AK143570,
AF483501,
U50372,
AC102176,
U50370,
M38700,
U50378,
U50375,
BC031422,
U34878,
AB010282,
Z14157,
U50373,
U50368,
AK146396,
U50367,
U50371
Ensembl:
ENSMUSG00000022471
KO:
mmu:14375
|
Nucleutide sequences |
EMBL-CDS:
AAH31422.1,
BAE27139.1,
BAE25441.1,
AAC53575.1,
AAC52675.1,
BAE27137.1,
BAA28874.1,
AAL90774.1,
AAA39396.1,
CAA78526.1,
AAL90775.1,
BAE27135.1
Ensembl_TRS:
ENSMUST00000069530,
ENSMUST00000100399
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000068559,
ENSMUSP00000097968
RefSeq:
XP_006520505.1,
XP_011243758.1,
NP_034377.2,
XP_006520506.1,
XP_006520507.1,
XP_006520508.1
|
Others |
UniRef100:
UniRef100_P23475,
UniRef100_A0A0R4J187
UniRef90:
UniRef90_P23475
UniRef50:
UniRef50_P12956
UniGene:
Mm.288809
CCDS:
CCDS37153.1
|