| Type | Description |
|---|---|
| Definition | Friend virus susceptibility 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-20 10:38:00 | Regions of Fv1 adapt cooperatively, highlighting its preference for repeated structures and suggesting that this functionally constrained aspect of the retroviral capsid lattice presents a common target in the evolution of intrinsic immunity. | 30224488 |
| 2017-05-06 11:03:00 | data indicate that for some but not all Fv1 proteins, gain of restriction activities could be achieved by increasing the expression level of Fv1; however such a concentration dependent effect is not seen with most Fv1s and cannot explain the recently reported activities against non-MLVs | 27342974 |
| 2014-11-08 13:45:00 | These results support the hypothesis that Fv1 defended mice against waves of retroviral infection | 24603659 |
| 2014-09-27 10:38:00 | The antiparallel organization of the NtD regions of Fv1 and Trim5alpha dimers correctly positions C-terminal specificity and N-terminal effector domains and facilitates stable binding to adjacent capsid hexamers in viral cores. | 24979782 |
| 2011-07-02 10:03:00 | Ordered assembly of murine leukemia virus capsid protein on lipid nanotubes directs specific binding by the restriction factor, Fv1. | 21436027 |
| Type | IDs |
|---|---|
| Synonymous | Fv-1, Rv-1, Rv1 |
| Gene |
UniProtKB-ID:
FV1_MOUSE
UniprotKB:
P70213
UniParc:
UPI000002308F
EMBL:
X97720,
X97719
Ensembl:
ENSMUSG00000070583
KO:
mmu:14349
|
| Nucleutide sequences |
EMBL-CDS:
CAA66306.1,
CAA66305.1
Ensembl_TRS:
ENSMUST00000094481
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000092054
RefSeq:
NP_034374.2
|
| Others |
UniRef100:
UniRef100_P70213
UniRef90:
UniRef90_P70213
UniRef50:
UniRef50_P70213
UniGene:
Mm.422607
CCDS:
CCDS38964.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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