| Type | Description |
|---|---|
| Definition | CDK2 associated cullin domain 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 12:22:00 | CAC1 plays an important role in the occurrence and promotion of antineoplastic drug resistance in colorectal cancer. CAC1 knockdown resulted in decreased P-glycoprotein and MRP-1 protein expression. | 31504073 |
| 2017-06-03 11:36:00 | These data suggest that CACUL1 is a novel regulator that negatively controls p53 activity through the regulation of PML SUMOylation. | 27889610 |
| 2017-02-18 12:18:00 | Suggest that CACUL1 impairs LSD1-mediated activation of AR, thereby implicating it as a potential antitumor target in prostate cancer cells. | 27085459 |
| 2016-10-01 11:18:00 | silencing CACUL1 resulted in the same effects of miR-106a* overexpression in esophageal carcinoma cells, including suppressed esophageal carcinoma cell proliferation and blocked G1/S transition through CDK2 pathway by inhibiting cell cycle regulators. | 26314198 |
| 2014-08-30 10:45:00 | H. pylori-triggered CACUL1 production occurred in an activating protein 1-dependent manner and regulated matrix metalloproteinase 9 and Slug expression to affect the invasion and metastasis of tumor cells. | 24004834 |
| Type | IDs |
|---|---|
| Synonymous | C10orf46, CAC1 |
| Gene |
UniProtKB-ID:
CACL1_HUMAN
UniprotKB:
Q86Y37
UniParc:
UPI000000DCD0,
UPI00000742F5,
UPI00000730AB
EMBL:
BC038294,
AY743663,
AL139407,
AK097728,
AJ544771
Ensembl:
ENSG00000151893
KO:
hsa:143384
|
| Nucleutide sequences |
EMBL-CDS:
AAU89709.1,
BAC05153.1,
CAD67614.1,
AAH38294.1
Ensembl_TRS:
ENST00000493518,
ENST00000369151
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000431329,
ENSP00000358147
RefSeq:
NP_722517.3
|
| Others |
UniRef100:
UniRef100_Q86Y37
UniRef90:
UniRef90_Q86Y37
UniRef50:
UniRef50_Q86Y37
UniGene:
Hs.420024
CCDS:
CCDS41570.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员