| Type | Description |
|---|---|
| Definition | ferritin light polypeptide 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 11:18:00 | iron overload due to impaired ferritinophagy or other cause(s) is likely to initiate prion-like spread of alpha-syn and ferritin, creating retinal iron dyshomeostasis and associated cytotoxicity. Since over-expression of alpha-syn is a known cause of Parkinson's disease. | 28993630 |
| 2018-03-03 11:55:00 | Ferritin is considered the major iron storage protein which maintains a large iron core in its cavity and has ferroxidase activity. (Review) | 28349628 |
| 2016-02-06 10:24:00 | Analysis of Ftl-/- mice revealed systemic and brain iron dyshomeostasis, without any noticeable signs of neurodegeneration. | 25629408 |
| 2013-09-28 11:20:00 | Noncoding G-to-T transversion (c.-168G>T) located in the iron response element (IRE) of the gene coding for ferritin light chain (FTL) cosegregated with cataract in the family. | 23592921 |
| 2010-10-30 10:30:00 | Hx plays an important role in controlling iron distribution within brain, thus suggesting its involvement in iron-related neurodegenerative diseases. | 19120692 |
| Type | IDs |
|---|---|
| Synonymous | Ftl, Ftl-1, L-ferritin |
| Gene |
UniProtKB-ID:
Q9CPX4_MOUSE
UniprotKB:
Q9CPX4
UniParc:
UPI0000026DD1
EMBL:
AK152564,
BC092259,
BC081462,
AK002253,
BC083350,
AC151602,
BC106146,
AK011009,
AK159574,
AK152385,
AK151255,
AK168866,
AK168862,
AK002242,
AK152030,
AK152612,
AK169159,
AK011244,
AK011029,
AK088647,
CT009486,
AK150480,
AK152393,
BC085309,
AK168735,
AK169100
Ensembl:
ENSMUSG00000062382,
ENSMUSG00000050708
KO:
mmu:14325,
mmu:100862446
|
| Nucleutide sequences |
EMBL-CDS:
BAE31173.1,
BAE40576.1,
BAE40681.1,
BAE40883.1,
AAH92259.1,
BAB27491.1,
BAE40938.1,
BAE40685.1,
BAB27328.1,
BAE31181.1,
BAE29596.1,
AAH85309.1,
BAB21967.1,
BAC40475.1,
BAB21959.1,
BAE31357.1,
AAH81462.1,
BAE31317.1,
BAE35195.1,
AAH83350.1,
BAB27345.1,
BAE30244.1,
AAI06147.1,
BAE30889.1
Ensembl_TRS:
ENSMUST00000222435,
ENSMUST00000094434
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000152609,
ENSMUSP00000092002
RefSeq:
NP_034370.2
|
| Others |
UniRef100:
UniRef100_Q9CPX4
UniRef90:
UniRef90_P29391
UniRef50:
UniRef50_P29391
UniGene:
Mm.30357,
Mm.348374,
Mm.431913,
Mm.491102
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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