| Type | Description |
|---|---|
| Definition | bromodomain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:58:00 | Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice. | 32559200 |
| 2019-12-21 10:12:00 | Ex vivo and cell-based assays revealed that Hdac11 catalytic activity suppresses the BAT transcriptional program, in both the basal state and in response to beta-adrenergic receptor signaling, through a mechanism that is dependent on physical association with Brd2. These findings define an epigenetic pathway for the regulation of energy homeostasis. | 30089714 |
| 2019-12-14 11:29:00 | Brd2 triggers insulin resistance via lipolysis-mediated free fatty acids release. | 31121164 |
| 2017-12-02 12:23:00 | these results provided evidence for a novel role of Brd2 in chronic inflammation and insulin resistance. | 27865874 |
| 2017-09-09 14:08:00 | BRD2 acts to augment the boundary function of CTCF both by limiting the spread or range of enhancer activity and by physically preventing the formation of cross-boundary contacts genome-wide. | 28388437 |
| Type | IDs |
|---|---|
| Synonymous | AW228947, D17H6S113E, Frg-1, Fsrg-1, Fsrg1, Nat, Ring3, Rnf3, mKIAA4005 |
| Gene |
UniProtKB-ID:
BRD2_MOUSE,
B2RS09_MOUSE
UniprotKB:
Q7JJ13,
B2RS09
UniParc:
UPI000016D1AF,
UPI0000022304
EMBL:
AB010248,
AK147918,
AK158970,
AK168525,
D89801,
KJ650222,
AF045462,
AL009226,
AK220444,
AB010247,
AB010246,
AF100956,
AF318183,
BC138656,
CR974462,
AB212273,
BC138655
Ensembl:
ENSMUSG00000024335
KO:
mmu:14312
|
| Nucleutide sequences |
EMBL-CDS:
CAA15818.1,
AAC24810.1,
BAE40404.1,
BAE34749.1,
BAA24378.1,
AAK07919.1,
BAA24377.1,
CAA15819.1,
AAC69907.1,
BAA24379.1,
BAD97682.1,
BAD90273.1,
BAE28228.1,
BAA25416.1,
CAM17898.1,
AIC84010.1,
AAI38657.1,
AAI38656.1
Gene_ORFName:
RP23-222K15.1-001
Ensembl_TRS:
ENSMUST00000095347,
ENSMUST00000025193,
ENSMUST00000114242
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025193,
ENSMUSP00000109880,
ENSMUSP00000092990
RefSeq:
XP_036016214.1,
NP_001191902.1,
XP_036016216.1,
XP_036016215.1,
XP_030105361.1,
XP_030105360.1,
XP_017172744.1,
NP_034368.2,
XP_030105359.1
|
| Others |
UniRef100:
UniRef100_Q7JJ13
UniRef90:
UniRef90_P25440
UniRef50:
UniRef50_P25440
UniGene:
Mm.3444
CCDS:
CCDS28641.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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