| Type | Description |
|---|---|
| Definition | neuronal calcium sensor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:26:00 | Contribution of neuronal calcium sensor 1 (Ncs-1) to anxiolytic-like and social behavior mediated by valproate and Gsk3 inhibition. | 32165725 |
| 2020-03-07 10:32:00 | NCS-1 knockout exacerbated nigral neurodegeneration and downregulated Cav2.3. Cav2.3 deficiency upregulated transcripts for NCS-1. | 31704946 |
| 2017-08-12 10:26:00 | Phosphorylation of CaMKII-alpha, known to trigger long-term potentiation and increase BDNF levels, was significantly reduced in the Ncs1-/- mouse brain. Further, electric potential stimulation, which increases the levels of BDNF and promotes spatial learning, significantly increased the levels of NCS-1 concomitant with phosphorylated CaMKII-alpha in the hippocampus; suggesting a close relationship between NCS-1 and CaM... | 28122057 |
| 2017-06-03 12:20:00 | these data demonstrate that NCS-1 contributes to stress tolerance in cardiomyocytes at least in part by activating certain Ca(2+)-dependent survival pathways that promote mitochondrial biosynthesis/function and detoxification pathways. | 27555477 |
| 2016-10-22 12:17:00 | These studies identify novel roles for NCS-1 in regulating activity-dependent striatal dopamine release and aspects of motivated behavior | 26738968 |
| Type | IDs |
|---|---|
| Synonymous | 9430075O15Rik, A730032G13Rik, AI836659, Freq, Mfreq, NCS-1 |
| Gene |
UniProtKB-ID:
NCS1_MOUSE
UniprotKB:
Q8BNY6
UniParc:
UPI00000000FB
EMBL:
AK079136,
AF020184,
BC059825,
AL732572
Ensembl:
ENSMUSG00000062661
KO:
mmu:14299
|
| Nucleutide sequences |
EMBL-CDS:
AAD01642.1,
AAH59825.1,
BAC37557.1
Ensembl_TRS:
ENSMUST00000000199
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000000199
RefSeq:
NP_062655.1
|
| Others |
UniRef100:
UniRef100_P62166
UniRef90:
UniRef90_P62166
UniRef50:
UniRef50_P62166
UniGene:
Mm.249318
CCDS:
CCDS15896.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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