| Type | Description |
|---|---|
| Definition | formyl peptide receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:27:00 | Modulation of NLRP3 Inflammasome through Formyl Peptide Receptor 1 (Fpr-1) Pathway as a New Therapeutic Target in Bronchiolitis Obliterans Syndrome. | 32244997 |
| 2019-11-16 12:06:00 | FPR1 is a plague receptor on immune cells in both humans and mice, and its absence or mutation provides protection against Y. pestis | 31534221 |
| 2019-08-24 11:05:00 | Fpr1 activation induces actin polymerization in wild type vascular smooth muscle cells. Absence of Fpr1 in the vasculature significantly decreased vascular contraction and induced loss of myogenic tone to elevated intraluminal pressures via disruption of actin polymerization. | 30639374 |
| 2019-06-29 11:07:00 | Mouse neutrophils lacking formyl peptide receptors (Fpr1/2(-/-)) are defective in the phagocytosis of Escherichia coli and the chemoattractant N-formyl-Met-Leu-Phe (fMLP)-coated beads. | 30540534 |
| 2018-09-01 10:48:00 | Study showed significantly increased expression of FPR1 and FPR2, during differentiation of neural stem cells (NSCs). The activation of FPRs promotes NSCs to differentiate into neurons with more primary neurites and branch points and longer neurites per cell. Meanwhile, this activation also inhibits the differentiation of NSCs into astrocytes. | 28303030 |
| Type | IDs |
|---|---|
| Synonymous | FPR, LXA4R, fMLF-R |
| Gene |
UniProtKB-ID:
FPR1_MOUSE
UniprotKB:
P33766
UniParc:
UPI00000210BF
EMBL:
AK137714,
CH466642,
L22181
Ensembl:
ENSMUSG00000045551
KO:
mmu:14293
|
| Nucleutide sequences |
EMBL-CDS:
AAA16110.1,
BAE23472.1,
EDL20512.1
Ensembl_TRS:
ENSMUST00000061516
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000052894
RefSeq:
NP_038549.1
|
| Others |
UniRef100:
UniRef100_P33766
UniRef90:
UniRef90_P33766
UniRef50:
UniRef50_P33766
UniGene:
Mm.56951
CCDS:
CCDS28418.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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