Fosb - FBJ osteosarcoma oncogene B-BMKCloudï½ç¾è¿å®¢äº

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14282 Fosb

基因描述

Type	Description
Definition	FBJ osteosarcoma oncogene B

研究结论

Date	Results	Publications
2020-09-26 13:09:00	Circuit-specific hippocampal DeltaFosB underlies resilience to stress-induced social avoidance.	32901027
2020-09-26 13:03:00	DeltaFosB Requires Galanin, but not Leptin, to Increase Bone Mass via the Hypothalamus, but both are needed to increase Energy expenditure.	30998833
2020-04-11 12:32:00	Using transgenic expression of mouse DeltaFosB in the striatum of parkinsonian primates, study shows that elevated levels of DeltaFosB lead to l-Dopa-induced dyskinesia (LID) development in the absence of chronic l-Dopa exposure. The physiological and molecular changes associated with LID are also replicated in this model. These findings suggest that DeltaFosB elevation is responsible for LID generation.	31455727
2019-12-28 11:49:00	Fosb expression in the hippocampal subgranular zone is necessary for both hippocampal neurogenesis and memory formation.	30902680
2019-11-02 10:57:00	data strongly support a dissociable cell-type-specific role for DeltaFosB in the nucleus accumbens in modulating aggression and aggression reward	29891732

名称对应

Type	IDs
Gene	UniProtKB-ID: FOSB_MOUSE, A0A140LIE4_MOUSE, A2RSD4_MOUSE UniprotKB: P13346, A0A140LIE4, A2RSD4 UniParc: UPI0000020D5B, UPI0003D70A32 EMBL: BC132064, X14897, BC137994, AF093624, AC148988 Ensembl: ENSMUSG00000003545 KO: mmu:14282
Nucleutide sequences	EMBL-CDS: AAD13196.1, CAA33026.1, AAI32065.1, AAI37995.1 Ensembl_TRS: ENSMUST00000003640, ENSMUST00000208446
Protein sequencees	Ensembl_PRO: ENSMUSP00000003640, ENSMUSP00000146789 RefSeq: NP_001334515.1, NP_032062.1
Others	UniRef100: UniRef100_P13346 UniRef90: UniRef90_P53539 UniRef50: UniRef50_P53539 UniGene: Mm.248335 CCDS: CCDS20897.1

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
32901027	Circuit-specific hippocampal ÎFosB underlies resilience to stress-induced social avoidance. Nat Commun Andrew L Eagle , Claire E Manning , Elizabeth S Williams , Ryan M Bastle , Paula A Gajewski , Amber Garrison , Alexis J Wirtz , Seda Akguen , Katie Brandel-Ankrapp , Wilson Endege , Frederick M Boyce , Yoshinori N Ohnishi , Michelle Mazei-Robison , Ian Maze , Rachel L Neve , Alfred J Robison	2020-09-08	-
32877400	Trappc9 deficiency causes parent-of-origin dependent microcephaly and obesity. PLoS Genet Zhengzheng S Liang , Irene Cimino , Binnaz Yalcin , Narayanan Raghupathy , Valerie E Vancollie , Ximena Ibarra-Soria , Helen V Firth , Debra Rimmington , I Sadaf Farooqi , Christopher J Lelliott , Steven C Munger , Stephen O'Rahilly , Anne C Ferguson-Smith , Anthony P Coll , Darren W Logan	2020-09-01	-
31455727	Role of striatal ÎFosB in l-Dopa-induced dyskinesias of parkinsonian nonhuman primates. Proc. Natl. Acad. Sci. U.S.A. Goichi Beck , Arun Singh , Jie Zhang , Lisa F Potts , Jong-Min Woo , Eun S Park , Hideki Mochizuki , M Maral Mouradian , Stella M Papa	2019-09-10	-
30998833	ÎFosB Requires Galanin, but not Leptin, to Increase Bone Mass via the Hypothalamus, but both are needed to increase Energy expenditure. J. Bone Miner. Res. Anna Idelevich , Kazusa Sato , Kenichi Nagano , Glenn Rowe , Francesca Gori , Roland Baron	2019-09-01	-
30902680	Hippocampal Subgranular Zone FosB Expression Is Critical for Neurogenesis and Learning. Neuroscience Claire E Manning , Andrew L Eagle , Christine C Kwiatkowski , Ridouane Achargui , Hillary Woodworth , Emily Potter , Yoshinori Ohnishi , Gina M Leinninger , A J Robison	2019-05-15	-
31291246	Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing. PLoS ONE Rajiv Kumar Sah , Analn Yang , Fatoumata Binta Bah , Salah Adlat , Ameer Ali Bohio , Zin Mar Oo , Chenhao Wang , May Zun Zaw Myint , Noor Bahadar , Luqing Zhang , Xuechao Feng , Yaowu Zheng	2019-01-01	-
29891732	Cell-Type-Specific Role of ÎFosB in Nucleus Accumbens In Modulating Intermale Aggression. J. Neurosci. Hossein Aleyasin , Meghan E Flanigan , Sam A Golden , Aki Takahashi , Caroline Menard , Madeline L Pfau , Jacob Multer , Jacqueline Pina , Kathryn A McCabe , Naemal Bhatti , Georgia E Hodes , Mitra Heshmati , Rachael L Neve , Eric J Nestler , Elizabeth A Heller , Scott J Russo	2018-06-27	-
28462942	Cell-Type-Specific Epigenetic Editing at the Fosb Gene Controls Susceptibility to Social Defeat Stress. Neuropsychopharmacology Peter J Hamilton , Dominika J Burek , Sonia I Lombroso , Rachael L Neve , Alfred J Robison , Eric J Nestler , Elizabeth A Heller	2018-01-01	-
29408867	Genome-wide profiling reveals functional diversification of âFosB gene targets in the hippocampus of an Alzheimer's disease mouse model. PLoS ONE Jason C You , Gabriel S Stephens , Chia-Hsuan Fu , Xiaohong Zhang , Yin Liu , Jeannie Chin	2018-01-01	-
29272704	AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection. Mol. Cell Thomas Vierbuchen , Emi Ling , Christopher J Cowley , Cameron H Couch , Xiaofeng Wang , David A Harmin , Charles W M Roberts , Michael E Greenberg	2017-12-21	-

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