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14264 Fmod

14264

Fmod

fibromodulin

protein-coding

Mus musculus

基因描述

Type Description
Definition fibromodulin

研究结论

Date Results Publications
2019-10-05 12:14:00 this study suggests that downregulation of miR-340-5p plays a role in promoting cell proliferation and suppressing cell apoptosis of chondrocytes in Osteoarthritis (OA) mice through inhibition of the ERK signaling pathway via the FMOD gene. 30144066
2019-06-29 10:33:00 our data indicates that Bgn and Fmod expressed by the bone forming cells, are novel coupling ECM components that control bone mass through sequestration of TNFalpha and/or RANKL, thereby adjusting their bioavailability in order to regulate osteoclastogenesis. 28974711
2019-01-19 12:16:00 The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling. 30052659
2018-12-22 11:22:00 FMOD affected the expressions of the Cav1.1 and Cav3.1 genes. FMOD regulates calcium channel activity. The mRNA expressions of Cav1.1 and Cav3.1 increased during muscle regeneration. 29913145
2018-10-27 11:27:00 Studies in knockout, obese, and diabetic mouse models helped characterize the operation of a novel FMOD-based regulatory circuit that controls myoblast switching from a myogenic to a lipid accumulation fate. FMOD regulation of myoblasts is an essential part of the myogenic program, and it offers opportunities for the development of therapeutics for the treatment of different muscle diseases 28974563

名称对应

Type IDs
Synonymous AI131919, AU041740, FM, SLRR2E
Gene
UniProtKB-ID: FMOD_MOUSE, Q543D2_MOUSE
UniprotKB: P50608, Q543D2
UniParc: UPI0000003FC3
EMBL: X94998, AK053317, AK032302, AK082593, BC064779, AK054183
Ensembl: ENSMUSG00000041559
KO: mmu:14264
Nucleutide sequences
EMBL-CDS: AAH64779.1, CAA64454.1, BAC35685.1, BAC27801.1, BAC38543.1, BAC35342.1
Ensembl_TRS: ENSMUST00000048183
Protein sequencees
Ensembl_PRO: ENSMUSP00000035489
RefSeq: NP_067330.1
Others
UniRef100: UniRef100_P50608
UniRef90: UniRef90_Q06828
UniRef50: UniRef50_Q06828
UniGene: Mm.287146
CCDS: CCDS15301.1

全选

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研究热度

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