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14262 Fmo3

14262

Fmo3

flavin containing monooxygenase 3

protein-coding

Mus musculus

基因描述

Type Description
Definition flavin containing monooxygenase 3

研究结论

Date Results Publications
2020-05-16 12:30:00 TMAO could be associated with increased hepatic Abcg5/g8 expression, biliary cholesterol hypersecretion and gallstone formation. 31251986
2019-12-28 12:13:00 Suppression of fmo3 by antisense oligonucleotides reduces TMAO levels, and platelet adhesion to matrix in whole blood under physiological sheer stress, but does not impact tail bleeding time. Host hepatic FMO3, the terminal step in the metaorganismal TMAO pathway, participates in diet-dependent and gut microbiota-dependent changes in both platelet responsiveness and thrombosis potential in vivo. 29981269
2019-10-05 10:46:00 our findings indicated that acrolein-enhanced atherogenesis by increasing FMO3 which increased inflammatory responses and decreased ABCA1 in vitro can be alleviated by Hydroxytyrosol (HT), which may have a therapeutic potential for the treatment of atherosclerosis. 29953618
2018-08-11 10:20:00 Diabetes induced the expression of both Fmo3 and ICAM expression and possible vascular impairment through enteric dysbiosis. Diabetes-induced Fmo3 and ICAM expression could be reversed by pJNK inhibition or by correcting enteric dysbiosis. 29851956
2018-06-16 11:53:00 The suppression of FMO3 metabolism related to reversible S-nitrosyl modifications of iNOS-derived NO in type 1 allergic mice. 28760731

名称对应

Type IDs
Synonymous AW111792
Gene
UniProtKB-ID: FMO3_MOUSE, Q3UEN4_MOUSE, Q8C7J1_MOUSE
UniprotKB: P97501, Q3UEN4, Q8C7J1
UniParc: UPI00000E99E7, UPI000002299F
EMBL: AK149440, AK050123, U87147
Ensembl: ENSMUSG00000026691
KO: mmu:14262
Nucleutide sequences
EMBL-CDS: AAB47541.1, BAE28877.1, BAC34077.1
Ensembl_TRS: ENSMUST00000028010
Protein sequencees
Ensembl_PRO: ENSMUSP00000028010
RefSeq: NP_032056.1
Others
UniRef100: UniRef100_P97501, UniRef100_Q8C7J1
UniRef90: UniRef90_Q8C7J1, UniRef90_Q9EQ76
UniRef50: UniRef50_G3WUW5, UniRef50_P31513
UniGene: Mm.2900
CCDS: CCDS15426.1

全选

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