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14256 Flt3l

14256

Flt3l

FMS-like tyrosine kinase 3 ligand

protein-coding

Mus musculus

基因描述

Type Description
Definition FMS-like tyrosine kinase 3 ligand

研究结论

Date Results Publications
2021-04-03 13:32:00 FLT3 Ligand Is Dispensable for the Final Stage of Type 1 Conventional Dendritic 32887750
2020-04-04 11:08:00 Study demonstrated that conventional dendritic cells 2 (cDC2s) produced their own FLT3L and utilized the transmembrane metalloproteinase ADAM10 to shed membrane bound FLT3L into soluble forms. This process was crucial for cDC2s to develop and survive in the spleen. These findings likely represent cell-autonomous developmental and survival processes that enable cDC2s to preferentially gain access to FLT3L. 31262819
2019-10-05 10:53:00 Data indicate that combined over-expression of interleukin 7 (IL-7) and FMS-like tyrosine kinase 3 ligand (FL) leads to a massive expansion of most bone marrow hematopoietic progenitors. 30364182
2019-08-17 10:37:00 Fms-Like Ligand Attenuates Local and Systemic Infection in a Model of Post-Burn Pneumonia. 28796661
2019-06-22 15:10:00 the discrepancy between Flt3(-/-) and Flt3l(-/-) mice results from the increased sensitivity of Flt3(-/-) progenitors to these cytokines. 29572360

名称对应

Type IDs
Synonymous Flt3lg, Ly72L
Gene
UniProtKB-ID: FLT3L_MOUSE, A9QW46_MOUSE
UniprotKB: P49772, A9QW46
UniParc: UPI000002A9BF, UPI000002A9C0, UPI0000003F42, UPI000002A9C1
EMBL: EU274583, S76464, AK020105, U44024, L23636, S76459, U29875, S76461, U04807
Ensembl: ENSMUSG00000110206
KO: mmu:14256
Nucleutide sequences
EMBL-CDS: AAA90952.1, AAA93307.1, AAA39436.1, AAA93306.1, AAB33070.1, AAA90951.1, AAA18000.1, AAB33069.1, AAB33071.1, BAB31997.1, ABX76044.1
Ensembl_TRS: ENSMUST00000146760, ENSMUST00000211246, ENSMUST00000209238
Protein sequencees
Ensembl_PRO: ENSMUSP00000147278, ENSMUSP00000123506, ENSMUSP00000148156
RefSeq: XP_036008564.1, XP_036008570.1, XP_006540672.1, NP_038548.3, XP_036008566.1, XP_006540673.1, XP_036008567.1, XP_036008563.1, XP_036008569.1, XP_030097993.1, XP_036008568.1, XP_006540675.1, XP_036008565.1
Others
UniRef100: UniRef100_P49772
UniRef90: UniRef90_P49772
UniRef50: UniRef50_P49772
UniGene: Mm.1658
CCDS: CCDS39948.1

全选

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