| Type | Description |
|---|---|
| Definition | filaggrin |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:15:00 | Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice. | 31479664 |
| 2020-08-01 10:48:00 | findings reveal a critical metabolic signaling relay of barrier formation in which epidermal mTORC2 activity controls FLG processing and de novo epidermal lipid synthesis during cornification. | 31401286 |
| 2020-07-11 12:43:00 | our FlgHrnr(-/-) mouse model nicely reflects the epicutaneous sensitization susceptibilities and inflammatory reactions to environmental insults in humans with impaired skin barrier functions. | 30828807 |
| 2020-05-02 11:41:00 | In vivo experiment, Chaenomeles sinensis administration reduced thickening of the epidermis and infiltration of inflammatory cells into the dermis as compared to 2,4-dinitrochlorobenzene (DNCB) treatment. Moreover, the decrease of filaggrin expression due to DNCB treatment was recovered by Chaenomeles sinensis administration. | 31839748 |
| 2020-04-04 10:38:00 | 3D in vivo imaging of the mCherry-K1 labeled bundled keratin filaments in mouse primary cultured keratinocytes from Flg-/- and Flg+/+ mice visualized keratin filament networks in living stratum granulosum (SG) cells and revealed the contribution of profilaggrin expression to the keratin network in SG cells of live mice. | 31167711 |
| Type | IDs |
|---|---|
| Synonymous | AW107830, ft |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
XP_017175331.1
|
| Others |
UniGene:
Mm.162684,
Mm.439710
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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