| Type | Description |
|---|---|
| Definition | forkhead box F2 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 11:16:00 | Knockout of Foxf1 and Foxf2 together, but not alone, from mouse smooth muscle resulted in delayed liquid gastric emptying | 30565344 |
| 2019-06-01 10:16:00 | Expression of the transcription factor forkhead box protein F2 (Foxf2) is upregulated during the epithelial to mesenchymal transition (EMT) process. | 30285803 |
| 2017-09-23 13:08:00 | direct targeting of Foxf2 by Shh signaling drives cranial neural crest cell mesenchyme proliferation during upper lip morphogenesis, and disruption of this sequence results in cleft lip. | 28506991 |
| 2017-06-24 11:27:00 | Foxf2(-/-) maxillary explants cultured in vitro, in the absence of tongue and mandible, failed to close the secondary palate. Proliferation and collagen content were decreased in Foxf2(-/-) palatal shelf mesenchyme. Phosphorylation of Smad2/3 was reduced in mutant palatal shelf, diagnostic of attenuated canonical Tgfbeta signaling, whereas phosphorylation of p38 was increased. | 27180663 |
| 2016-05-14 11:49:00 | novel Shh-Foxf-Fgf18-Shh circuit in the palate development molecular network, in which Foxf1 and Foxf2 regulate palatal shelf growth downstream of Shh signaling, at least in part, by repressing Fgf18 expression | 26745863 |
| Type | IDs |
|---|---|
| Synonymous | FREAC2, Fkh20, LUN |
| Gene |
UniProtKB-ID:
FOXF2_MOUSE
UniprotKB:
O54743
UniParc:
UPI0000025428
EMBL:
Y12294,
Y12293,
BC137947,
AK132385,
BC137949,
Y11148
Ensembl:
ENSMUSG00000038402
KO:
mmu:14238
|
| Nucleutide sequences |
EMBL-CDS:
AAI37948.1,
CAA72972.1,
BAE21137.1,
CAA72035.1,
AAI37950.1
Ensembl_TRS:
ENSMUST00000042054
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000046789
RefSeq:
NP_034355.2
|
| Others |
UniRef100:
UniRef100_O54743
UniRef90:
UniRef90_O54743
UniRef50:
UniRef50_Q12947
UniGene:
Mm.125548
CCDS:
CCDS26424.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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