| Type | Description |
|---|---|
| Definition | FK506 binding protein 1a |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:56:00 | FKBP12: A partner of Snx10 required for vesicular trafficking in osteoclasts. | 30887568 |
| 2019-12-28 12:30:00 | cardiomyocyte-restricted overexpression of FKBP12 reduces the atrial Nav1.5 expression level and mean peak INa, which is associated with increased peak L-type Ca(2+) current and interstitial fibrosis in atria. The combined electrophysiological and structural changes facilitated the development of local conduction block and altered action potential duration and spontaneous AF. | 30499712 |
| 2017-11-25 15:40:00 | Acute tacrolimus treatment transiently increases hepcidin in wild-type mice. FKBP12 preferentially targets the BMP receptor ALK2. ALK2 mutants defective in binding FKBP12 increase hepcidin expression in a ligand-independent manner, through BMP-SMAD signaling. | 28864813 |
| 2016-11-19 11:53:00 | FKBP51 is a central mediator of chronic pain. | 26865567 |
| 2015-02-21 10:46:00 | We demonstrate that FKBP12 and its ligands impact multiple aspects of muscle function. | 25053409 |
| Type | IDs |
|---|---|
| Synonymous | FKBP12, Fkbp, Fkbp1 |
| Gene |
UniProtKB-ID:
FKB1A_MOUSE,
Q1JUQ8_MOUSE,
Q3UKJ3_MOUSE,
Q1JUQ7_MOUSE
UniprotKB:
P26883,
Q1JUQ8,
Q3UKJ3,
Q1JUQ7
UniParc:
UPI0000D77DDB,
UPI0000D77DDC,
UPI000000186F,
UPI00003561B2
EMBL:
AK002777,
AK010693,
AF483489,
AK019362,
AB241120,
U65100,
X60203,
AK154751,
AK145986,
AK169186,
U65098,
AB241121,
AF483488,
AK168333,
BC004671,
U65099,
AK169242
Ensembl:
ENSMUSG00000032966
KO:
mmu:14225
|
| Nucleutide sequences |
EMBL-CDS:
BAE40271.1,
BAE32804.1,
BAB31680.1,
AAB17554.1,
BAB27125.1,
BAE41008.1,
BAE40963.1,
CAA42762.1,
AAL90762.1,
AAL90763.1,
BAB22351.1,
AAH04671.1,
BAE94232.1,
BAE26808.1,
BAE94233.1
Ensembl_TRS:
ENSMUST00000044011
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000037206
RefSeq:
NP_001289006.1,
NP_001289009.1,
NP_001289007.1,
NP_001342007.1,
NP_001289008.1,
NP_001342006.1,
NP_032045.1
|
| Others |
UniRef100:
UniRef100_Q3UKJ3,
UniRef100_P26883,
UniRef100_Q1JUQ8,
UniRef100_Q1JUQ7
UniRef90:
UniRef90_Q1JUQ8,
UniRef90_Q1JUQ7,
UniRef90_P26883,
UniRef90_Q3UKJ3
UniRef50:
UniRef50_P26883,
UniRef50_Q1JUQ8,
UniRef50_Q3UKJ3,
UniRef50_Q1JUQ3
UniGene:
Mm.278458,
Mm.487732
CCDS:
CCDS16869.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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