| Type | Description |
|---|---|
| Definition | four and a half LIM domains 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:31:00 | Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury. | 31963815 |
| 2020-12-05 13:03:00 | FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy. | 31040292 |
| 2020-10-24 14:00:00 | LIM-only protein FHL2 attenuates inflammation in vascular smooth muscle cells through inhibition of the NFkappaB pathway. | 31866461 |
| 2020-05-30 12:53:00 | FHL2 plays a role in wound healing and inflammation. It seems to be involved in numerous steps of these extremely complex and multidirectional but tightly regulated tissue remodeling processes, supporting tissue repair and coordinating inflammation. Deficiency of FHL2 not only slows down ongoing wound healing but also often turns it into a chronic condition. Review. | 30939249 |
| 2019-12-14 11:43:00 | FHL2 is involved in renal interstitial fibrosis by altering the phenotype of renal tubular epithelial cells via regulating the beta-catenin pathway. | 29771425 |
| Type | IDs |
|---|---|
| Synonymous | FHL-2, SLIM-3, SLIM3 |
| Gene |
UniProtKB-ID:
FHL2_MOUSE,
Q543D7_MOUSE
UniprotKB:
O70433,
Q543D7
UniParc:
UPI00000040D1
EMBL:
U77040,
AK052936,
AK147024,
AF153340,
AF055889,
AF114381
Ensembl:
ENSMUSG00000008136
KO:
mmu:14200
|
| Nucleutide sequences |
EMBL-CDS:
AAD53230.1,
AAC12770.1,
AAD34170.1,
AAB19211.2,
BAE27617.1,
BAC35211.1
Ensembl_TRS:
ENSMUST00000008280,
ENSMUST00000185893
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000141170,
ENSMUSP00000008280
RefSeq:
NP_001276462.1,
XP_011236736.1,
NP_034342.1
|
| Others |
UniRef100:
UniRef100_O70433
UniRef90:
UniRef90_O70433
UniRef50:
UniRef50_O70433
UniGene:
Mm.6799
CCDS:
CCDS14922.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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