| Type | Description |
|---|---|
| Definition | fragile histidine triad gene |
| Date | Results | Publications |
|---|---|---|
| 2017-02-18 12:28:00 | Fhit loss and subsequent thymidine kinase 1 inactivation, combined with selective pressures, leads to neoplasia-associated alterations in genes and gene expression patterns in vitro and in vivo | 27513973 |
| 2016-08-27 12:40:00 | Fhit-deficiency mutation signature also resembles a C>T and T>C mutation signature reported for human papillary kidney cancers and a similar signature recently reported for esophageal and bladder cancers, cancers that are frequently Fhit deficient. | 26782170 |
| 2015-02-28 13:30:00 | Fhit deficiency-induced global genome instability promotes mutation and clonal expansion | 24244712 |
| 2014-08-09 12:23:00 | Fhit delocalizes annexin A4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel. | 24223161 |
| 2014-03-01 12:34:00 | FHIT gene is a "caretaker gene" necessary for maintenance of genome stability. | 23929738 |
| Type | IDs |
|---|---|
| Synonymous | AW045638, Fra14A2 |
| Gene |
UniProtKB-ID:
FHIT_MOUSE,
E9PZ91_MOUSE
UniprotKB:
O89106,
E9PZ91
UniParc:
UPI0001DD340C,
UPI00000298B1
EMBL:
AL589696,
BC012662,
AC105071,
AC159306,
AF055573,
AC154776,
AC158979,
AH013372,
AC154197,
AC154360,
AH006186,
AC154570,
AC102431,
CT485999,
AF047699
Ensembl:
ENSMUSG00000060579
KO:
mmu:14198
|
| Nucleutide sequences |
EMBL-CDS:
AAC23967.1,
AAC24117.1,
AAR17701.1,
AAC24566.1,
AAH12662.1
Ensembl_TRS:
ENSMUST00000162278,
ENSMUST00000161302,
ENSMUST00000179394,
ENSMUST00000160340
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000124073,
ENSMUSP00000123874,
ENSMUSP00000136011,
ENSMUSP00000124017
RefSeq:
XP_036014357.1,
NP_001295214.1,
XP_036014355.1,
XP_036014356.1,
XP_011243034.1,
NP_001295215.1,
NP_034340.1,
NP_001347070.1,
XP_006517987.1,
XP_030103509.1
|
| Others |
UniRef100:
UniRef100_O89106
UniRef90:
UniRef90_O89106
UniRef50:
UniRef50_O89106
UniGene:
Mm.397619,
Mm.441926
CCDS:
CCDS49400.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员