| Type | Description |
|---|---|
| Definition | FGR proto-oncogene, Src family tyrosine kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:33:00 | Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity. | 32943786 |
| 2019-11-02 12:16:00 | A loss of a single Src family kinase, Fgr or Lyn, reduced platelet-mediated monocyte recruitment in vitro and a significant reduction in the burden of atherosclerotic disease in Fgr(-/-) /ApoE(-/-) or Lyn(-/-) /ApoE(-/-) animals. | 29974666 |
| 2017-08-05 10:45:00 | the Hck, Fgr and Lyn kinases are also necessary for amastigote uptake by macrophages. Src-mediated Arg activation is required for efficient uptake. | 27358479 |
| 2015-12-19 11:54:00 | Data indicate that Src-Family Kinases Hck and Fgr regulate cytokine secretion by macrophages. | 26232427 |
| 2015-11-07 11:49:00 | Fgr is not only are progressively overexpressed in atherosclerosis, but it also controls critical molecular processes in monocyte influx, blood monocyte subset balance, macrophage accumulation, and the maintenance of atherosclerotic lesion stability. | 26068045 |
| Type | IDs |
|---|---|
| Synonymous | Ali18, Mhdaali18 |
| Gene |
UniProtKB-ID:
FGR_MOUSE
UniprotKB:
P14234
UniParc:
UPI0000023018
EMBL:
AL627184,
X52191,
AK038141,
AK036438,
X16440,
AK155902,
AK036476,
CH466552
Ensembl:
ENSMUSG00000028874
KO:
mmu:14191
|
| Nucleutide sequences |
EMBL-CDS:
BAC29429.1,
BAE33493.1,
EDL30082.1,
EDL30081.1,
CAA36437.1,
BAC29445.1,
BAC29939.1,
CAA34463.1
Ensembl_TRS:
ENSMUST00000171223,
ENSMUST00000030693
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030693,
ENSMUSP00000128411
RefSeq:
XP_006538607.1,
NP_034338.3,
XP_006538608.1
|
| Others |
UniRef100:
UniRef100_P14234
UniRef90:
UniRef90_P14234
UniRef50:
UniRef50_P14234
UniGene:
Mm.271665
CCDS:
CCDS18739.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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