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14186 Fgfr4

14186

Fgfr4

fibroblast growth factor receptor 4

protein-coding

Mus musculus

基因描述

Type Description
Definition fibroblast growth factor receptor 4

研究结论

Date Results Publications
2021-01-23 12:56:00 FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice. 31758962
2020-10-31 13:18:00 FGFR4 does not contribute to progression of chronic kidney disease. 31575945
2020-05-09 13:31:00 In mice receiving normal chow, the FGFR4 Arg385 allele was associated with elevated hepatic triglyceride content, altered hepatic lipid composition, and increased hepatic expression of genes inducing de novo lipogenesis and glycolysis. Body fat mass and distribution, glucose tolerance, and insulin sensitivity were unaltered. The FGFR4 Arg385 allele had no effect on glucose or lipid metabolism under the high-fat diet. 30541128
2019-10-12 12:47:00 The synergistic effects of TGFbeta2, WNT9a, and FGFR4 were responsible for attenuating of the differentiation of aging satellite cells during skeletal muscle development. 29869452
2018-12-22 11:26:00 our data highlight a role of FGF23/FGFR4 signaling in the regulation of cardiac remodeling and function, and indicate that pharmacological interference with cardiac FGF23/FGFR4 signaling might protect from CKD- and age-related LVH. 28512310

名称对应

Type IDs
Synonymous Fgfr-4
Gene
UniProtKB-ID: FGFR4_MOUSE, A0A0R4IZY3_MOUSE
UniprotKB: Q03142, A0A0R4IZY3
UniParc: UPI00006C2108, UPI0000693C7A, UPI0000020E99
EMBL: AK084850, DQ388428, X59927, BC033313, AY493377, X57236, AC123709
Ensembl: ENSMUSG00000005320
KO: mmu:14186
Nucleutide sequences
EMBL-CDS: AAS72387.2, CAA40512.1, AAH33313.1, CAA42551.1, ABD43187.1, BAC39292.1
Ensembl_TRS: ENSMUST00000005452
Protein sequencees
Ensembl_PRO: ENSMUSP00000005452
RefSeq: NP_032037.2, XP_006517162.3, XP_006517163.1
Others
UniRef100: UniRef100_Q03142, UniRef100_A0A0R4IZY3
UniRef90: UniRef90_Q03142
UniRef50: UniRef50_Q03142
UniGene: Mm.276715
CCDS: CCDS26540.1

全选

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研究热度

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