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14174 Fgf3

14174

Fgf3

fibroblast growth factor 3

protein-coding

Mus musculus

基因描述

Type Description
Definition fibroblast growth factor 3

研究结论

Date Results Publications
2017-12-16 12:24:00 results indicate that Fgf3 hypomethylation and gene overexpression, but not protein expression, occurred in the early stage of oral carcinogenesis induced by DBP 29073177
2017-05-27 11:43:00 We demonstrate that elevated BMP4 depletes PSM progenitors in vitro, phenocopying the Fgf3 mutant, suggesting that excessive BMP signals cause the Fgf3 axis defect. To test this in vivo we increased BMP signaling in Fgf3 mutants by removing one copy of Noggin, which encodes a BMP antagonist. 27144312
2013-12-14 11:26:00 FGF signaling sustains the odontogenic fate of dental mesenchyme by suppressing beta-catenin signaling. 24067353
2013-03-23 11:09:00 Ectopic expression of Fgf3 leads to aberrant lineage segregation in the mouse parthenote preimplantation embryos. 22930543
2013-03-02 13:12:00 Data suggest that Fgf3/Fgfr3 signaling is required for maintenance of Gnrh (gonadotropin-releasing hormone) neurons in aging hypothalamus; postnatal Gnrh system is plastic/resilient, able to override preexisting defects and respond to external cues. 23047985

名称对应

Type IDs
Synonymous Fgf-3, Int-2, Int-P
Gene
UniProtKB-ID: Q0VG15_MOUSE
UniprotKB: Q0VG15
UniParc: UPI000002368D
EMBL: BC117061, BC117059, AC149593
Ensembl: ENSMUSG00000031074
KO: mmu:14174
Nucleutide sequences
EMBL-CDS: AAI17062.1, AAI17060.1
Ensembl_TRS: ENSMUST00000105898
Protein sequencees
Ensembl_PRO: ENSMUSP00000101518
RefSeq: NP_032033.2
Others
UniRef100: UniRef100_Q0VG15
UniRef90: UniRef90_P05524
UniRef50: UniRef50_P48802
UniGene: Mm.4947

全选

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研究热度

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