| Type | Description |
|---|---|
| Definition | fibroblast growth factor 18 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:12:00 | The Fgf8 subfamily (Fgf8, Fgf17 and Fgf18) is required for closure of the embryonic ventral body wall. | 32907848 |
| 2020-07-04 11:00:00 | Using a novel Fgf18:CreERT2 allele to lineage trace alveolar myofibroblast, it is demonstrated that most alveolar myofibroblast are developmentally cleared during alveologenesis. | 31862844 |
| 2018-12-01 10:04:00 | Study found that Fgf18 mRNA was one of the spinal motor neurons (SMNs)-specific FGFs in adult mice. Fgf18 mRNA was expressed in the spinal cord, and to a lesser extent in the diaphragm, in mouse embryos. In C2C12 myotubes, FGF18 enhanced AChR clustering. These data propose that FGF18 plays a pivotal role in AChR clustering and NMJ formation in mouse embryogenesis. | 29323161 |
| 2017-05-13 21:50:00 | Elevation of FGF signaling, mainly due to increased Fgf18 expression upon inactivation of Evc2 in the perichondrium, critically contributes to the pathogenesis of limb dwarfism. The limb dwarfism phenotype is partially rescued by inactivation of one allele of Fgf18 in the Evc2 mutant mice | 28027321 |
| 2016-08-06 11:15:00 | Loss of alleles of Fgf9 and Fgf18 also affect the expression of genes encoding other key intrinsic skeletal regulators, including IHH, PTHLH (PTHrP), and RUNX2, revealing potential direct, indirect, and compensatory mechanisms to coordinate chondrogenesis and osteogenesis. | 26794256 |
| Type | IDs |
|---|---|
| Synonymous | D130055P09Rik, FGF-18 |
| Gene |
UniProtKB-ID:
FGF18_MOUSE
UniprotKB:
O89101
UniParc:
UPI00000298B0
EMBL:
AF211187,
AB004639,
AF075291
Ensembl:
ENSMUSG00000057967
KO:
mmu:14172
|
| Nucleutide sequences |
EMBL-CDS:
AAF22976.1,
BAA31980.1,
AAC62239.1
Ensembl_TRS:
ENSMUST00000020507
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020507
RefSeq:
NP_032031.1
|
| Others |
UniRef100:
UniRef100_O89101
UniRef90:
UniRef90_O89101
UniRef50:
UniRef50_O76093
UniGene:
Mm.339812
CCDS:
CCDS24531.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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