| Type | Description |
|---|---|
| Definition | ferredoxin reductase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:31:00 | Integrated analysis of the molecular pathogenesis of FDXR-associated disease. | 32499495 |
| 2020-11-21 13:32:00 | FDXR regulates TP73 tumor suppressor via IRP2 to modulate aging and tumor suppression. | 32304229 |
| 2018-12-22 10:03:00 | These data provide further insight into the pathogenic mechanism of FDXR-mediated central neuropathy, and suggest an avenue for mechanistic studies that will ultimately inform treatment. | 30250212 |
| 2018-09-01 10:44:00 | FDXR and p53 are mutually regulated and that the FDXR-p53 loop is critical for tumor suppression via iron homeostasis. | 28747430 |
| Type | IDs |
|---|---|
| Synonymous | AR |
| Gene |
UniProtKB-ID:
ADRO_MOUSE
UniprotKB:
Q61578
UniParc:
UPI00000289EA
EMBL:
D49920
Ensembl:
ENSMUSG00000018861
KO:
mmu:14149
|
| Nucleutide sequences |
EMBL-CDS:
BAA08659.1
Ensembl_TRS:
ENSMUST00000021078
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000021078
RefSeq:
XP_006532249.1,
NP_032023.1
|
| Others |
UniRef100:
UniRef100_Q61578
UniRef90:
UniRef90_Q61578
UniRef50:
UniRef50_P22570
UniGene:
Mm.4719
CCDS:
CCDS25625.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32304229 |
FDXR regulates TP73 tumor suppressor via IRP2 to modulate aging and tumor suppression. J Pathol Jin Zhang , Xiangmudong Kong , Yanhong Zhang , Wenqiang Sun , Jian Wang , Mingyi Chen , Xinbin Chen |
2020-07-01 | - |
| 32499495 |
Integrated analysis of the molecular pathogenesis of FDXR-associated disease. Cell Death Dis Jesse D Slone , Li Yang , Yanyan Peng , Luis F Queme , Belinda Harris , Stacey J Sukoff Rizzo , Torrian Green , Jennifer L Ryan , Michael P Jankowski , Laura G Reinholdt , Taosheng Huang |
2020-06-04 | - |
| 32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
| 30550785 |
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Cell Hyeonwoo Kim , Christiane D Wrann , Mark Jedrychowski , Sara Vidoni , Yukiko Kitase , Kenichi Nagano , Chenhe Zhou , Joshua Chou , Virginia-Jeni A Parkman , Scott J Novick , Timothy S Strutzenberg , Bruce D Pascal , Phuong T Le , Daniel J Brooks , Alexander M Roche , Kaitlyn K Gerber , Laura Mattheis , Wenjing Chen , Hua Tu , Mary L Bouxsein , Patrick R Griffin , Roland Baron , Clifford J Rosen , Lynda F Bonewald , Bruce M Spiegelman |
2018-12-13 | - |
| 30250212 |
Biallelic mutations in FDXR cause neurodegeneration associated with inflammation. J. Hum. Genet. Jesse Slone , Yanyan Peng , Adam Chamberlin , Belinda Harris , Julie Kaylor , Marie T McDonald , Monica Lemmon , Mays Antonine El-Dairi , Dmitry Tchapyjnikov , Laura A Gonzalez-Krellwitz , Elizabeth A Sellars , Allyn McConkie-Rosell , Laura G Reinholdt , Taosheng Huang |
2018-12-01 | - |
| 29040572 |
Hum. Mol. Genet. Yanyan Peng , Deepali N Shinde , C Alexander Valencia , Jun-Song Mo , Jill Rosenfeld , Megan Truitt Cho , Adam Chamberlin , Zhuo Li , Jie Liu , Baoheng Gui , Rachel Brockhage , Alice Basinger , Brenda Alvarez-Leon , Peter Heydemann , Pilar L Magoulas , Andrea M Lewis , Fernando Scaglia , Solange Gril , Shuk Ching Chong , Matthew Bower , Kristin G Monaghan , Rebecca Willaert , Maria-Renee Plona , Rich Dineen , Francisca Milan , George Hoganson , Zoe Powis , Katherine L Helbig , Jennifer Keller-Ramey , Belinda Harris , Laura C Anderson , Torrian Green , Stacey J Sukoff Rizzo , Julie Kaylor , Jiani Chen , Min-Xin Guan , Elizabeth Sellars , Steven P Sparagana , James B Gibson , Laura G Reinholdt , Sha Tang , Taosheng Huang |
2017-12-15 | - |
| 28747430 |
Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2. Genes Dev Yanhong Zhang , Yingjuan Qian , Jin Zhang , Wensheng Yan , Yong-Sam Jung , Mingyi Chen , Eric Huang , Kent Lloyd , Yuyou Duan , Jian Wang , Gang Liu , Xinbin Chen |
2017-06-15 | - |
| 25917818 |
Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. Genome Res Heather Fairfield , Anuj Srivastava , Guruprasad Ananda , Rangjiao Liu , Martin Kircher , Anuradha Lakshminarayana , Belinda S Harris , Son Yong Karst , Louise A Dionne , Coleen C Kane , Michelle Curtain , Melissa L Berry , Patricia F Ward-Bailey , Ian Greenstein , Candice Byers , Anne Czechanski , Jocelyn Sharp , Kristina Palmer , Polyxeni Gudis , Whitney Martin , Abby Tadenev , Laurent Bogdanik , C Herbert Pratt , Bo Chang , David G Schroeder , Gregory A Cox , Paul Cliften , Jeffrey Milbrandt , Stephen Murray , Robert Burgess , David E Bergstrom , Leah Rae Donahue , Hanan Hamamy , Amira Masri , Federico A Santoni , Periklis Makrythanasis , Stylianos E Antonarakis , Jay Shendure , Laura G Reinholdt |
2015-07-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 18614015 |
A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha |
2008-07-11 |
Acacb,
Hscb,
Gadd45gip1,
Lars2,
Acad11,
Chchd10,
Nt5dc3,
Slc25a41,
Nt5m,
Cyp27a1,
Acly,
Ndufb11,
Gldc,
Rexo2,
Rars,
Aldh6a1,
Slc25a47,
Rdh14,
Ppif,
Ldhal6b,
Me2,
Glyat,
Slc25a45,
Acaca,
Nt5c3,
Mrpl10,
Mrpl41,
Mrpl30,
Aldh1l1,
Mthfs,
Shmt2,
Atic,
Mthfd1,
Mat2b,
Fam210a,
Gpt2,
Lyrm2,
Rdh13,
Mtrf1l,
Atad3a,
Rars2,
Sccpdh,
Me3,
Maob,
Dut,
Cyp11b1,
Fdps,
Akr7a5,
Msra,
Krt5,
Cox6b1,
Qdpr,
Acat1,
Acat2,
Aldh7a1,
Pcca,
Etfb,
Etfa,
Nudt19,
Acadl,
Acadm,
Acadvl,
Acaa1a,
Acads,
Aco1,
Aco2,
Prosc,
Afg3l1,
Adsl,
Agxt,
Ak2,
Ak4,
Akap1,
Alas1,
Alas2,
Abcd1,
Aldh2,
Aldh3a2,
Gfer,
Acsm1,
Slc25a4,
Slc25a5,
Prdx3,
Prdx6,
Mrps2,
Arg2,
Rhoa,
Atp5a1,
Atp5b,
Atp5c1,
Atp5f1,
Atp5g1,
Atp5j,
Atp5k,
Atpif1,
Auh,
Akr1b7,
Bad,
Bak1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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