| Type | Description |
|---|---|
| Definition | ficolin A |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:27:00 | FCN-A mediates the inflammatory response and the macrophage polarization in Aspergillus fumigatus keratitis of mice by activating the MAPK signaling pathway. | 32272397 |
| 2019-05-11 10:17:00 | Lipopolysaccharide-induced inflammation can induce a significant ficolin response. | 30818229 |
| 2017-11-26 01:15:00 | Ficolin-2 induces macrophage activation, promotes M1 polarization and facilitates proliferation and antigen-specific cytotoxicity of CD8(+) T cells. Ficolin-2 binds to Toll-like receptor 4 (TLR4) on macrophages and DCs and promotes their antigen-presenting abilities to CD8(+) T cells. | 28844702 |
| 2017-10-14 12:38:00 | this study demonstrates that ficolins are important in initial innate host defense against Aspergillus fumigatus infections in vivo | 27467404 |
| 2017-09-16 11:49:00 | this study shows that FCN-A/2 exacerbated the inflammatory pathogenesis of inflammatory bowel disease by stimulating M1 polarization through the TLR4/MyD88/MAPK/NF-kappaB signalling pathway in macrophages | 28380665 |
| Type | IDs |
|---|---|
| Synonymous | Fcn1 |
| Gene |
UniProtKB-ID:
FCN1_MOUSE,
Q4FJM1_MOUSE
UniprotKB:
O70165,
Q4FJM1
UniParc:
UPI0000022A5F
EMBL:
BC019180,
AK133539,
AK159651,
CT010383,
AK138752,
AB007813
Ensembl:
ENSMUSG00000026938
KO:
mmu:14133
|
| Nucleutide sequences |
EMBL-CDS:
AAH19180.1,
BAA25126.1,
BAE23769.1,
BAE35262.1,
CAJ18590.1,
BAE21714.1
Ensembl_TRS:
ENSMUST00000028307
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028307
RefSeq:
NP_032021.1,
XP_006497738.1,
XP_006497736.1,
XP_011237318.1
|
| Others |
UniRef100:
UniRef100_O70165
UniRef90:
UniRef90_O70165
UniRef50:
UniRef50_O70165
UniGene:
Mm.10510
CCDS:
CCDS15785.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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