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14132 Fcgrt

14132

Fcgrt

Fc receptor, IgG, alpha chain transporter

protein-coding

Mus musculus

基因描述

Type Description
Definition Fc receptor, IgG, alpha chain transporter

研究结论

Date Results Publications
2021-01-16 16:01:00 Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of glomerulonephritis. 33370294
2020-09-26 13:07:00 FcRn mediates fast recycling of endocytosed albumin and IgG from early macropinosomes in primary macrophages. 31444284
2020-04-11 12:34:00 In podocytes, Fcgrt modulates the IL-6 mediated response to inflammatory stimuli and regulates podocytes actin structure. 31553647
2020-02-15 12:55:00 The studies demonstrate a pivotal role for FcRn-mediated salvage in compensating for the high pinocytic and degradative activities of macrophages to maintain IgG homeostasis. 30964743
2019-11-09 11:44:00 Knockout of FcRn leads to IgG accumulation in podocytes but does not alter albumin trafficking. 30811433

名称对应

Type IDs
Synonymous FcRn
Gene
UniProtKB-ID: FCGRN_MOUSE
UniprotKB: Q61559
UniParc: UPI0000020D35
EMBL: D37913, D37907, D37905, L17022, D37903, D37874, D37873, D37911, D37909
Ensembl: ENSMUSG00000003420
KO: mmu:14132
Nucleutide sequences
EMBL-CDS: BAA07139.1, BAA07138.1, BAA07136.1, BAA07110.1, BAA07137.1, BAA07134.1, BAA07111.1, AAA16904.1, BAA07135.1
Ensembl_TRS: ENSMUST00000003512
Protein sequencees
Ensembl_PRO: ENSMUSP00000003512
RefSeq: NP_001344046.1, NP_034319.2
Others
UniRef100: UniRef100_Q61559
UniRef90: UniRef90_P13599
UniRef50: UniRef50_P13599
UniGene: Mm.3303
CCDS: CCDS52243.1

全选

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研究热度

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