| Type | Description |
|---|---|
| Definition | fibulin 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-13 12:45:00 | High FBLN2 expression is associated with cognitive impairment. | 30118321 |
| 2019-05-11 13:19:00 | Fibulin 2 localized to the RPE, choroid, and Bruch's membrane. Knockout mice had a significantly reduced scotopic A response by 1 month of age, when compared to their wild-type counterparts, which remained throughout life and only declined as a result of normal aging. The functional decline was associated with reduced number of photoreceptor cells. | 29721953 |
| 2017-06-24 10:58:00 | Our study indicates that Ang II cannot induce TGF-beta activation without fibulin-2 and that fibulin-2 has an essential role in Ang II-induced TGF-beta signaling and subsequent myocardial fibrosis. Fibulin-2 can be considered as a critical regulator of TGF-beta that induces myocardial fibrosis. | 27111286 |
| 2014-12-20 11:02:00 | These findings demonstrate a prominent role for alpha3beta1 in immortalized/transformed keratinocytes in regulating fibulin-2 and other genes that promote matrix remodeling and invasion. | 24694902 |
| 2014-11-22 11:15:00 | FBLN2 and VCAN were both preferentially expressed in the mammary gland during times of epithelial expansion in TEB-enriched tissue and co-localised specifically in cap cell. | 24522256 |
| Type | IDs |
|---|---|
| Synonymous | 5730577E14Rik, FIBL-2 |
| Gene |
UniProtKB-ID:
FBLN2_MOUSE,
Q3TGL4_MOUSE
UniprotKB:
P37889,
Q3TGL4
UniParc:
UPI0000F0A5D2,
UPI00005B24E0
EMBL:
AK168688,
AF135242,
AF135243,
AF135245,
AF135253,
AF135252,
X75285,
AF135250,
AC131764,
AF135241,
AF135249,
AC121990,
AF135248,
AF135240,
AF135251,
AF135239,
AF135247,
AF135246,
AF135244,
CH466523
Ensembl:
ENSMUSG00000064080
KO:
mmu:14115
|
| Nucleutide sequences |
EMBL-CDS:
EDK99296.1,
AAD34456.1,
CAA53040.1,
BAE40534.1
Ensembl_TRS:
ENSMUST00000041544,
ENSMUST00000113498
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000048334,
ENSMUSP00000109126
RefSeq:
XP_030111017.1,
XP_030111016.1,
XP_006505593.1,
NP_001074906.1,
NP_032018.2
|
| Others |
UniRef100:
UniRef100_P37889,
UniRef100_Q3TGL4
UniRef90:
UniRef90_P37889
UniRef50:
UniRef50_P98095
UniGene:
Mm.249146,
Mm.410235
CCDS:
CCDS39567.1,
CCDS39566.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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