| Type | Description |
|---|---|
| Definition | FAT atypical cadherin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:51:00 | Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis. | 33328637 |
| 2019-04-20 11:11:00 | coordinates the coupling of muscular and neuronal morphogenesis by playing distinct but complementary actions in several cell types | 29768404 |
| 2017-04-01 12:14:00 | studies suggest that Fat1 controls mitochondrial activity to restrain cell growth during the reparative, proliferative state induced by vascular injury. Given recent reports linking Fat1 to cancer, abnormal kidney and muscle development, and neuropsychiatric disease, this Fat1 function may have importance in other settings of altered cell growth and metabolism | 27828948 |
| 2016-07-16 11:04:00 | Fat1 deletion in podocytes induces abnormal glomerular filtration barrier development leading to podocyte foot process effacement. Fat1 knockdown in renal tubular cells reduces migration, decreases active RAC1/CDC42 and induces defects in lumen formation. | 26905694 |
| 2015-11-07 11:50:00 | Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development. | 26209645 |
| Type | IDs |
|---|---|
| Synonymous | 2310038E12Rik, AU023433, Fath, mFat1 |
| Gene |
UniProtKB-ID:
A0A087WRT4_MOUSE,
F2Z4A3_MOUSE,
A0A1L1SQU7_MOUSE
UniprotKB:
A0A087WRT4,
F2Z4A3,
A0A1L1SQU7
UniParc:
UPI000050B507,
UPI0003D786FE,
UPI000050B508
EMBL:
AC158352,
AC119214
Ensembl:
ENSMUSG00000070047
KO:
mmu:14107
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000189017,
ENSMUST00000098796,
ENSMUST00000191428,
ENSMUST00000215588
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000140765,
ENSMUSP00000096394,
ENSMUSP00000140596,
ENSMUSP00000149194
RefSeq:
XP_006509336.1,
XP_006509334.1,
NP_001074755.2,
XP_036009649.1,
XP_036009648.1,
XP_006509331.1,
XP_006509337.1,
XP_006509340.1,
XP_030099147.1,
XP_017168053.1,
XP_006509335.1,
XP_036009647.1,
XP_030099148.1,
XP_006509333.1,
XP_006509339.1,
XP_006509330.1,
XP_011240475.1
|
| Others |
UniRef100:
UniRef100_A0A1L1SQU7,
UniRef100_F2Z4A3,
UniRef100_A0A087WRT4
UniRef90:
UniRef90_Q9QXA3
UniRef50:
UniRef50_Q14517
UniGene:
Mm.27365
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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