| Type | Description |
|---|---|
| Definition | DNA cross-link repair 1B |
| Date | Results | Publications |
|---|---|---|
| 2012-09-22 10:22:00 | Study documents the combinatorial action of Apollo, POT1b, CST, and the 5' exonuclease Exo1 in postreplicative telomere end processing in mouse cells, clarifying the mechanism by which the telomeric 3' overhang is generated and modulated. | 22748632 |
| 2011-03-12 11:26:00 | The telomeric protein SNM1B/Apollo is required for normal cell proliferation and embryonic development | 20854421 |
| 2010-09-27 12:28:00 | TRF2-bound Apollo functions at replicating telomeres, promoting the maintenance of the telomeric overhang, repressing S phase-specific ATM signaling, and protecting leading-end telomeres from fusion. | 20619712 |
| 2010-08-09 12:18:00 | Apollo null mouse embryo fibroblasts exhibit an increased incidence of G2 chromatid-type fusions involving telomeres created by leading-strand DNA synthesis, reflective of a failure to protect these telomeres after DNA replication. | 20551906 |
| Type | IDs |
|---|---|
| Synonymous | AI452214, Apollo, SNMIB, mSNM1B |
| Gene |
UniProtKB-ID:
DCR1B_MOUSE
UniprotKB:
Q8C7W7
UniParc:
UPI00001F0A51,
UPI00001F0A54,
UPI00000EAEEC
EMBL:
AK046571,
BC067017,
AK049115,
BC011094,
CU210953,
AK154124,
AK134324,
AK084347,
BC125277,
AK137495,
AK138568
Ensembl:
ENSMUSG00000027845
KO:
mmu:140917
|
| Nucleutide sequences |
EMBL-CDS:
BAE23700.1,
AAH67017.1,
BAC39165.1,
AAI25278.1,
BAC33550.1,
BAC32791.1,
BAE22098.1,
AAH11094.1,
BAE23379.1,
BAE32389.1
Ensembl_TRS:
ENSMUST00000106832,
ENSMUST00000063502,
ENSMUST00000106834,
ENSMUST00000029435
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000067695,
ENSMUSP00000102445,
ENSMUSP00000029435,
ENSMUSP00000102447
RefSeq:
NP_001020483.1,
NP_598626.2
|
| Others |
UniRef100:
UniRef100_Q8C7W7
UniRef90:
UniRef90_Q8C7W7
UniRef50:
UniRef50_Q9H816
UniGene:
Mm.374850
CCDS:
CCDS17695.1,
CCDS17694.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 22748632 |
Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST. Cell Peng Wu , Hiroyuki Takai , Titia de Lange |
2012-07-06 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20854421 |
Aging Cell Shamima Akhter , Yung C Lam , Sandy Chang , Randy J Legerski |
2010-12-01 | - |
| 20619712 |
Apollo contributes to G overhang maintenance and protects leading-end telomeres. Mol Cell Peng Wu , Megan van Overbeek , Sean Rooney , Titia de Lange |
2010-08-27 | - |
| 20551906 |
SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair. EMBO J Yung C Lam , Shamima Akhter , Peili Gu , Jing Ye , Anaïs Poulet , Marie-Josèphe Giraud-Panis , Susan M Bailey , Eric Gilson , Randy J Legerski , Sandy Chang |
2010-07-07 | - |
| 18848520 |
SNM1A acts downstream of ATM to promote the G1 cell cycle checkpoint. Biochem. Biophys. Res. Commun. Shamima Akhter , Randy J Legerski |
2008-12-05 | - |
| 16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 16033648 |
BMC Dev. Biol. Adrienne E McKee , Emmanuel Minet , Charlene Stern , Shervin Riahi , Charles D Stiles , Pamela A Silver |
2005-01-01 |
Tdrd7,
Klhl3,
Rpl5,
Tra2a,
Sf3b3,
Slc6a8,
Scaf8,
Sf3b4,
Celf4,
Srsf9,
U2af1,
Ankhd1,
Rbm15b,
Adarb1,
Hdlbp,
Srsf1,
Adam5,
Akap1,
Tgs1,
Hnrnpd,
Cirbp,
Cnbp,
Col4a3,
Cpeb1,
Celf1,
Dazl,
Dhx9,
Ddx19a,
Eif4a1,
Khdrbs3,
Celf2,
Ewsr1,
Igf2bp1,
Igf2bp3,
Dclre1b,
Srsf10,
Fmr1,
Fxr1,
Thumpd3,
Hnrnpc,
Hnrnpa1,
Hnrnpab,
Hnrnpk,
Hnrnpl,
Prmt2,
Prmt1,
Trmt2a,
Elavl1,
Elavl2,
Elavl3,
Elavl4,
Ilf3,
Uhmk1,
Peg10,
Nxf7,
Khdrbs2,
Rbm39,
Ppargc1b,
Vmn1r26,
Msi1,
Myef2,
Ncl,
Ncoa3,
Zfp638,
Pabpc1,
Pabpc2,
Pcbp2,
Pdcd11,
Ppargc1a,
Scand1,
Nup88,
Eif2ak2,
Ptbp1,
Prpf8,
Qk,
Raly,
Rbm3,
Rbm4,
Rbm6,
Rbmx,
Rbmxl1,
Rbmy,
Rbpms,
Rn7sk,
Rnps1,
Polr1b,
Sub1,
Khdrbs1,
Srsf2,
Srsf5,
Tra2b,
Snrnp70,
Snrpb2,
Snrpe,
Son,
Rbms3,
Strbp,
Esrp1,
Setd1b
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员